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Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans
Advanced glycation end products (AGEs) are formed when glucose reacts nonenzymatically with proteins; these modifications are implicated in aging and pathogenesis of many age-related diseases including type II diabetes, atherosclerosis, and neurodegenerative disorders. Thus, pharmaceutical intervent...
Autores principales: | Golegaonkar, Sandeep, Tabrez, Syed S, Pandit, Awadhesh, Sethurathinam, Shalini, Jagadeeshaprasad, Mashanipalya G, Bansode, Sneha, Sampathkumar, Srinivasa-Gopalan, Kulkarni, Mahesh J, Mukhopadhyay, Arnab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406675/ https://www.ncbi.nlm.nih.gov/pubmed/25720500 http://dx.doi.org/10.1111/acel.12327 |
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