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Left Ventricular Systolic Dysfunction in Asymptomatic Marfan Syndrome Patients Is Related to the Severity of Gene Mutation: Insights from the Novel Three Dimensional Speckle Tracking Echocardiography

BACKGROUND: In asymptomatic Marfan syndrome (MFS) patients we evaluated the relationship between the types of fibrillin-1 (FBN1) gene mutation and possible altered left ventricular (LV) function as assessed by three-dimensional speckle tracking echocardiography (3D-STE). METHODS AND RESULTS: Forty-f...

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Detalles Bibliográficos
Autores principales: Abd El Rahman, Mohamed, Haase, Denise, Rentzsch, Axel, Olchvary, Julia, Schäfers, Hans-Joachim, Henn, Wolfram, Wagenpfeil, Stefan, Abdul-Khaliq, Hashim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406686/
https://www.ncbi.nlm.nih.gov/pubmed/25901601
http://dx.doi.org/10.1371/journal.pone.0124112