Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation

The MYC transcription factor plays a crucial role in the regulation of cell cycle progression, apoptosis, angiogenesis, and cellular transformation. Due to its oncogenic activities and overexpression in a majority of human cancers, it is an interesting target for novel drug therapies. MYC binding to...

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Detalles Bibliográficos
Autores principales: Mishra, Rajeev, Watanabe, Takayoshi, Kimura, Makoto T, Koshikawa, Nobuko, Ikeda, Maki, Uekusa, Shota, Kawashima, Hiroyuki, Wang, Xiaofei, Igarashi, Jun, Choudhury, Diptiman, Grandori, Carla, Kemp, Christopher J, Ohira, Miki, Verma, Narendra K, Kobayashi, Yujin, Takeuchi, Jin, Koshinaga, Tsugumichi, Nemoto, Norimichi, Fukuda, Noboru, Soma, Masayoshi, Kusafuka, Takeshi, Fujiwara, Kyoko, Nagase, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406810/
https://www.ncbi.nlm.nih.gov/pubmed/25611295
http://dx.doi.org/10.1111/cas.12610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406810/
https://www.ncbi.nlm.nih.gov/pubmed/25611295
http://dx.doi.org/10.1111/cas.12610

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