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The mechanisms of action of vaccines containing aluminum adjuvants: an in vitro vs in vivo paradigm
Adjuvants such as the aluminum compounds (alum) have been dominantly used in many vaccines due to their immunopotentiation and safety records since 1920s. However, how these mineral agents influence the immune response to vaccination remains elusive. Many hypotheses exist as to the mode of action of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406982/ https://www.ncbi.nlm.nih.gov/pubmed/25932368 http://dx.doi.org/10.1186/s40064-015-0972-0 |