Increased systemic exposures of artemether and dihydroartemisinin in infants under 5 kg with uncomplicated Plasmodium falciparum malaria treated with artemether-lumefantrine (Coartem®)

BACKGROUND: Artemether-lumefantrine (AL) dispersible formulation was developed for the treatment of uncomplicated Plasmodium falciparum malaria in infants and children weighing 5 to <35 kg. However, there are no clinical studies with artemisinin-based combination therapy in infants <5 kg. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Tiono, Alfred B, Tinto, Halidou, Alao, Maroufou J, Meremikwu, Martin, Tshefu, Antoinette, Ogutu, Bernhards, Ouedraogo, Alphonse, Lingani, Moussa, Cousin, Marc, Lefèvre, Gilbert, Jain, Jay Prakash, Duparc, Stephan, Hamed, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407414/
https://www.ncbi.nlm.nih.gov/pubmed/25886021
http://dx.doi.org/10.1186/s12936-015-0682-7

Ejemplares similares

Ejemplares similares