B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway

BACKGROUND: B7-homologue 3 (B7-H3), a recently identified immunoregulatory protein, has been shown to be overexpressed in human hepatocellular carcinoma (HCC). However, whether the dynamic expression pattern of B7-H3 contributes to early invasion of HCC is largely unknown. In addition, the biologica...

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Detalles Bibliográficos
Autores principales: Kang, Fu-biao, Wang, Ling, Jia, Heng-chuan, Li, Dong, Li, Hai-jun, Zhang, Yin-ge, Sun, Dian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407415/
https://www.ncbi.nlm.nih.gov/pubmed/25908926
http://dx.doi.org/10.1186/s12935-015-0195-z

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