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Optimal Molecular Methods in Detecting p190(BCR-ABL) Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature

Patients with BCR-ABL1 positive hematologic malignancies and Philadelphia-like B-lymphoblastic leukemia (B-ALL) are potential candidates for targeted therapy with tyrosine kinase inhibitors (TKI). Before TKIs, patients with B-ALL had a much worse prognosis and current treatments with targeted TKI th...

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Detalles Bibliográficos
Autores principales: Sonu, Rebecca J., Jonas, Brian A., Dwyre, Denis M., Gregg, Jeffrey P., Rashidi, Hooman H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407518/
https://www.ncbi.nlm.nih.gov/pubmed/25949834
http://dx.doi.org/10.1155/2015/458052