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Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro
BACKGROUND: Neuro-inflammation has long been implicated as a contributor to the progression of Alzheimer’s disease in both humans and animal models. Type-1 interferons (IFNs) are pleiotropic cytokines critical in mediating the innate immune pro-inflammatory response. The production of type-1 IFNs fo...
Autores principales: | Minter, Myles Robert, Main, Bevan Scott, Brody, Kate Maree, Zhang, Moses, Taylor, Juliet Marie, Crack, Peter John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407532/ https://www.ncbi.nlm.nih.gov/pubmed/25879763 http://dx.doi.org/10.1186/s12974-015-0263-2 |
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