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Valproic acid attenuates intercellular adhesion molecule-1 and E-selectin through a chemokine ligand 5 dependent mechanism and subarachnoid hemorrhage induced vasospasm in a rat model
BACKGROUND: Up-regulation of regulated upon activation, normal T-cell expressed and secreted (RANTES/CCL5) and adhesion molecules is observed in the serum of animals following experimental subarachnoid hemorrhage (SAH). The present study was to examine the effect of valproic acid (VPA) on RANTES and...
Autores principales: | Chang, Chih-Zen, Wu, Shu-Chuan, Lin, Chih-Lung, Kwan, Aij-Lie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407545/ https://www.ncbi.nlm.nih.gov/pubmed/25908928 http://dx.doi.org/10.1186/s12950-015-0074-3 |
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