Cargando…

Sphingosine 1-phosphate signaling pathway in inner ear biology. New therapeutic strategies for hearing loss?

Hearing loss is one of the most prevalent conditions around the world, in particular among people over 60 years old. Thus, an increase of this affection is predicted as result of the aging process in our population. In this context, it is important to further explore the function of molecular target...

Descripción completa

Detalles Bibliográficos
Autores principales:	Romero-Guevara, Ricardo, Cencetti, Francesca, Donati, Chiara, Bruni, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407579/ https://www.ncbi.nlm.nih.gov/pubmed/25954197 http://dx.doi.org/10.3389/fnagi.2015.00060

Ejemplares similares

Sphingosine 1-phosphate axis: a new leader actor in skeletal muscle biology
por: Donati, Chiara, et al.
Publicado: (2013)

Sphingosine kinase/sphingosine 1-phosphate axis: a new player for insulin-like growth factor-1-induced myoblast differentiation
por: Bernacchioni, Caterina, et al.
Publicado: (2012)

A(2)(B) Adenosine Receptors and Sphingosine 1-Phosphate Signaling Cross-Talk in Oligodendrogliogenesis
por: Coppi, Elisabetta, et al.
Publicado: (2021)

Sphingosine 1‐phosphate attenuates neuronal dysfunction induced by amyloid‐β oligomers through endocytic internalization of NMDA receptors
por: Bigi, Alessandra, et al.
Publicado: (2022)

Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes
por: Bernacchioni, Caterina, et al.
Publicado: (2021)

Sphingosine 1-Phosphate Induces Differentiation of Mesoangioblasts towards Smooth Muscle. A Role for GATA6
por: Donati, Chiara, et al.
Publicado: (2011)

Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P(3) Axis
por: Cencetti, Francesca, et al.
Publicado: (2010)

NMR metabolomics highlights sphingosine kinase‐1 as a new molecular switch in the orchestration of aberrant metabolic phenotype in cancer cells
por: Bernacchioni, Caterina, et al.
Publicado: (2017)

Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics
por: Vlajkovic, Srdjan M., et al.
Publicado: (2021)

Inner ear therapeutics and the war on hearing loss: systemic barriers to success
por: Jiam, Nicole T., et al.
Publicado: (2023)

Navigating Hereditary Hearing Loss: Pathology of the Inner Ear
por: Nicolson, Teresa
Publicado: (2021)

The TRPV1 Receptor Is Up-Regulated by Sphingosine 1-Phosphate and Is Implicated in the Anandamide-Dependent Regulation of Mitochondrial Activity in C2C12 Myoblasts
por: Standoli, Sara, et al.
Publicado: (2022)

Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss
por: Okano, Takayuki
Publicado: (2014)

Ceramide 1-phosphate stimulates proliferation of C2C12 myoblasts
por: Gangoiti, Patricia, et al.
Publicado: (2012)

Lysophosphatidic Acid Signaling Axis Mediates Ceramide 1-Phosphate-Induced Proliferation of C2C12 Myoblasts
por: Bernacchioni, Caterina, et al.
Publicado: (2018)

Radiological diagnosis of the inner ear malformations in children with sensorineural hearing loss
por: Quirk, Bernadine, et al.
Publicado: (2019)

Inflammasome activation in mouse inner ear in response to MCMV induced hearing loss
por: Shi, Xi, et al.
Publicado: (2015)

mTOR Signaling in the Inner Ear as Potential Target to Treat Hearing Loss
por: Cortada, Maurizio, et al.
Publicado: (2021)

Inner Ear Drug Delivery for Sensorineural Hearing Loss: Current Challenges and Opportunities
por: Liu, Sophie S., et al.
Publicado: (2022)

Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss
por: Mauriac, Stephanie A., et al.
Publicado: (2022)

Expression and function of pannexins in the inner ear and hearing
por: Zhao, Hong-Bo
Publicado: (2016)

Cannabinoids, Inner Ear, Hearing, and Tinnitus: A Neuroimmunological Perspective
por: Perin, Paola, et al.
Publicado: (2020)

Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear
por: Sato, Mitsuo P., et al.
Publicado: (2017)

The Relationship Between the Third Window Abnormalities and Inner Ear Malformations in Children with Hearing Loss
por: Ceren Sarioglu, Fatma, et al.
Publicado: (2021)

Vestibular Imaging and Function in Patients With Inner Ear Malformation Presenting With Profound Hearing Loss
por: Dy, Alexander Edward S., et al.
Publicado: (2022)

Murine CMV-Induced Hearing Loss Is Associated with Inner Ear Inflammation and Loss of Spiral Ganglia Neurons
por: Bradford, Russell D., et al.
Publicado: (2015)

Role of Cyclic Nucleotide Phosphodiesterases in Inner Ear and Hearing
por: Mittal, Rahul, et al.
Publicado: (2017)

Experimental Study of Local Inner Ear Gene Therapy for Controlling Autoimmune Sensorineural Hearing Loss
por: Tan, Chang-qiang, et al.
Publicado: (2014)

Sudden sensorineural hearing loss associated with inner ear lesions detected by magnetic resonance imaging
por: Cho, Jiwon, et al.
Publicado: (2017)

Application of Mesenchymal Stem Cell Therapy and Inner Ear Regeneration for Hearing Loss: A Review
por: Kanzaki, Sho, et al.
Publicado: (2020)

Advances and challenges in adeno-associated viral inner-ear gene therapy for sensorineural hearing loss
por: Bankoti, Kamakshi, et al.
Publicado: (2021)

Effect of shock wave power spectrum on the inner ear pathophysiology in blast-induced hearing loss
por: Kimura, Eiko, et al.
Publicado: (2021)

Hear, Hear for Notch: Control of Cell Fates in the Inner Ear by Notch Signaling
por: Brown, Rogers, et al.
Publicado: (2020)

Inner Ear Therapeutics: An Overview of Middle Ear Delivery
por: Patel, Jaimin, et al.
Publicado: (2019)

Imaging of sensorineural hearing loss: a pattern-based approach to diseases of the inner ear and cerebellopontine angle
por: Verbist, Berit M.
Publicado: (2011)

Retracted: Experimental Study of Local Inner Ear Gene Therapy for Controlling Autoimmune Sensorineural Hearing Loss
por: International, BioMed Research
Publicado: (2017)

Inner ear salivary gland choristoma extending to the middle ear with congenital profound hearing loss and facial palsy: a case report
por: Yamanobe, Yoshiharu, et al.
Publicado: (2021)

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Idiopathic sensorineural hearing loss in the only hearing ear
por: Berrettini, S., et al.
Publicado: (2016)

Neurobiology of Hearing Loss and Ear Disease
por: Park, Yong-Ho, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_c55vqtbvv2fpgqcnnb8bnqulc1