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DNA repair mechanisms in cancer development and therapy

DNA damage has been long recognized as causal factor for cancer development. When erroneous DNA repair leads to mutations or chromosomal aberrations affecting oncogenes and tumor suppressor genes, cells undergo malignant transformation resulting in cancerous growth. Genetic defects can predispose to...

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Detalles Bibliográficos
Autores principales:	Torgovnick, Alessandro, Schumacher, Björn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407582/ https://www.ncbi.nlm.nih.gov/pubmed/25954303 http://dx.doi.org/10.3389/fgene.2015.00157

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