Cargando…

Diallyl trisulfide inhibits migration, invasion and angiogenesis of human colon cancer HT-29 cells and umbilical vein endothelial cells, and suppresses murine xenograft tumour growth

Angiogenesis inhibitors are beneficial for the prevention and treatment of angiogenesis-dependent diseases including cancer. We examined the cytotoxic, anti-metastatic, anti-cancer and anti-angiogenic effects of diallyl trisulfide (DATS). In HT29 cells, DATS inhibited migration and invasion through...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Kuang-Chi, Hsu, Shu-Chun, Yang, Jai-Sing, Yu, Chien-Chih, Lein, Jin-Cherng, Chung, Jing-Gung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407594/ https://www.ncbi.nlm.nih.gov/pubmed/25403643 http://dx.doi.org/10.1111/jcmm.12486

Ejemplares similares

Dietary Bioactive Diallyl Trisulfide in Cancer Prevention and Treatment
por: Puccinelli, Michael T., et al.
Publicado: (2017)

Antimicrobial Effect and the Mechanism of Diallyl Trisulfide against Campylobacter jejuni
por: Tang, Yuanyue, et al.
Publicado: (2021)

Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps
por: Dong, Chengji, et al.
Publicado: (2022)

Breast Cancer Selective Disruption of Actin Cytoskeleton by Diallyl Trisulfide
por: Hahm, Eun-Ryeong, et al.
Publicado: (2022)

Exploring the role and mechanisms of diallyl trisulfide and diallyl disulfide in chronic constriction-induced neuropathic pain in rats
por: Wang, Gang, et al.
Publicado: (2020)

Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer
por: Malla, RamaRao, et al.
Publicado: (2022)

Diallyl Trisulfide Promotes Placental Angiogenesis by Regulating Lipid Metabolism and Alleviating Inflammatory Responses in Obese Pregnant Mice
por: Wang, Miaomiao, et al.
Publicado: (2022)

Treatment of Saos-2 osteosarcoma cells with diallyl trisulfide is associated with an increase in calreticulin expression
por: Xie, Wen-Peng, et al.
Publicado: (2018)

Reversion of P-Glycoprotein-Mediated Multidrug Resistance in Human Leukemic Cell Line by Diallyl Trisulfide
por: Xia, Qing, et al.
Publicado: (2012)

Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis
por: Hahm, Eun-Ryeong, et al.
Publicado: (2021)

Diallyl trisulfide plays an antifibrotic role by inhibiting the expression of Bcl‐2 in hepatic stellate cells
por: Pang, Huai, et al.
Publicado: (2022)

Effect of Diallyl Trisulfide on Ischemic Tissue Injury and Revascularization in a Diabetic Mouse Model
por: Yang, Hai-Bing, et al.
Publicado: (2018)

Effect of Diallyl Trisulfide on the Reproductive Behavior of the Grain Moth, Sitotroga cerealella (Lepidoptera: Gelechiidae)
por: Chang, Meng-Meng, et al.
Publicado: (2019)

Garlic Derived Diallyl Trisulfide in Experimental Metabolic Syndrome: Metabolic Effects and Cardioprotective Role
por: Jeremic, Jovana N., et al.
Publicado: (2020)

Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats
por: Hahm, Eun-Ryeong, et al.
Publicado: (2022)

Diallyl Trisulfide Suppresses Oxidative Stress-Induced Activation of Hepatic Stellate Cells through Production of Hydrogen Sulfide
por: Zhang, Feng, et al.
Publicado: (2017)

Increased Sulfiredoxin Expression in Gastric Cancer Cells May Be a Molecular Target of the Anticancer Component Diallyl Trisulfide
por: Wang, Juan, et al.
Publicado: (2019)

Diallyl Trisulfide Induces Apoptosis in Breast Ductal Carcinoma In Situ Derived and Minimally Invasive Breast Cancer Cells
por: Stan, Silvia D., et al.
Publicado: (2022)

Diallyl Trisulfide Inhibits Growth of NCI-H460 in Vitro and in Vivo, and Ameliorates Cisplatin-Induced Oxidative Injury in the Treatment of Lung Carcinoma in Xenograft Mice
por: Jiang, Xiaoyan, et al.
Publicado: (2017)

Diallyl Trisulfide Causes Male Infertility with Oligoasthenoteratospermia in Sitotroga cerealella through the Ubiquitin–Proteasome Pathway
por: Shah, Sakhawat, et al.
Publicado: (2023)

Apoptosis induction of U937 human leukemia cells by diallyl trisulfide induces through generation of reactive oxygen species
por: Choi, Yung Hyun, et al.
Publicado: (2012)

Keap1 Cysteine 288 as a Potential Target for Diallyl Trisulfide-Induced Nrf2 Activation
por: Kim, Sanghyun, et al.
Publicado: (2014)

Diallyl trisulfide attenuates hyperglycemia-induced endothelial apoptosis by inhibition of Drp1-mediated mitochondrial fission
por: Hao, Ying, et al.
Publicado: (2019)

Diallyl Trisulfide, the Antifungal Component of Garlic Essential Oil and the Bioactivity of Its Nanoemulsions Formed by Spontaneous Emulsification
por: Gong, Xue, et al.
Publicado: (2021)

Folic Acid Functionalized Diallyl Trisulfide–Solid Lipid Nanoparticles for Targeting Triple Negative Breast Cancer
por: De, Anindita, et al.
Publicado: (2023)

Diallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc
por: Borkowska, Andzelika, et al.
Publicado: (2011)

Inhibiting Invasion into Human Bladder Carcinoma 5637 Cells with Diallyl Trisulfide by Inhibiting Matrix Metalloproteinase Activities and Tightening Tight Junctions
por: Shin, Dong Yeok, et al.
Publicado: (2013)

Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation
por: Hsieh, Dennis Jine-Yuan, et al.
Publicado: (2020)

Diallyl trisulfide improves spinal cord ischemia–reperfusion injury damage by activating AMPK to stabilize mitochondrial function
por: Sun, Yang, et al.
Publicado: (2023)

Activation of PI3K/Akt mediates the protective effect of diallyl trisulfide on doxorubicin induced cardiac apoptosis
por: Wen, Su-Ying, et al.
Publicado: (2023)

Involvement of adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 in diallyl trisulfide-induced cytotoxicity in hepatocellular carcinoma cells
por: Guan, Feng, et al.
Publicado: (2022)

Diallyl Trisulfide Protects Rat Brain Tissue against the Damage Induced by Ischemia-Reperfusion through the Nrf2 Pathway
por: Silva-Islas, Carlos A., et al.
Publicado: (2019)

Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo
por: Ming, Le, et al.
Publicado: (2021)

Diallyl trisulfide alleviates chemotherapy sensitivity of ovarian cancer via the AMPK/SIRT1/PGC1α pathway
por: Wang, Zhaojun, et al.
Publicado: (2022)

Prediction of the mechanism for the combination of diallyl trisulfide and cisplatin against gastric cancer: a network pharmacology study and pharmacological evaluation
por: Lv, Huaiyou, et al.
Publicado: (2023)

Experimental study of inhibitory effects of diallyl trisulfide on the growth of human osteosarcoma Saos-2 cells by downregulating expression of glucose-regulated protein 78
por: Zhang, Yue, et al.
Publicado: (2018)

Effects of Diallyl Trisulfide, an Active Substance from Garlic Essential Oil, on Energy Metabolism in Male Moth Sitotroga cerealella (Olivier)
por: Wu, Meng-Ya, et al.
Publicado: (2020)

The Mitochondrial Ca(2+) Overload via Voltage-Gated Ca(2+) Entry Contributes to an Anti-Melanoma Effect of Diallyl Trisulfide
por: Nakagawa, Chinatsu, et al.
Publicado: (2020)

Diallyl Trisulfide Inhibits Leptin-induced Oncogenic Signaling in Human Breast Cancer Cells but Fails to Prevent Chemically-induced Luminal-type Cancer in Rats
por: Kim, Su-Hyeong, et al.
Publicado: (2020)

Diallyl trisulfide inhibited tobacco smoke-mediated bladder EMT and cancer stem cell marker expression via the NF-κB pathway in vivo
por: Geng, Hao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ofkg94kha384570rfdo95g2heq