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TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo

Toll-like receptors (TLRs) are a family of highly conserved transmembrane proteins expressed in epithelial and immune cells that recognize pathogen associated molecular patterns. Besides their role in immune response against infections, numerous studies have shown an important role of different TLRs...

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Detalles Bibliográficos
Autores principales: Gambara, Guido, Desideri, Marianna, Stoppacciaro, Antonella, Padula, Fabrizio, De Cesaris, Paola, Starace, Donatella, Tubaro, Andrea, del Bufalo, Donatella, Filippini, Antonio, Ziparo, Elio, Riccioli, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407608/
https://www.ncbi.nlm.nih.gov/pubmed/25444175
http://dx.doi.org/10.1111/jcmm.12379

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