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Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002

The Hedgehog (Hh) signaling pathway not only plays important roles in embryogenesis and adult tissue homeostasis, but also in tumorigenesis. Aberrant Hh pathway activation has been reported in a variety of malignant tumors including colon carcinoma. Here, we sought to investigate the regulation of t...

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Detalles Bibliográficos
Autores principales:	Cai, Xinyi, Yu, Kun, Zhang, Lijuan, Li, Yunfeng, Li, Qiang, Yang, Zhibin, Shen, Tao, Duan, Lincan, Xiong, Wei, Wang, Weiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407746/ https://www.ncbi.nlm.nih.gov/pubmed/25945059 http://dx.doi.org/10.2147/OTT.S71034

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