Cargando…

Semaphorin3a Promotes Advanced Diabetic Nephropathy

The onset of diabetic nephropathy (DN) is highlighted by glomerular filtration barrier abnormalities. Identifying pathogenic factors and targetable pathways driving DN is crucial to developing novel therapies and improving the disease outcome. Semaphorin3a (sema3a) is a guidance protein secreted by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aggarwal, Pardeep K., Veron, Delma, Thomas, David B., Siegel, Dionicio, Moeckel, Gilbert, Kashgarian, Michael, Tufro, Alda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407856/ https://www.ncbi.nlm.nih.gov/pubmed/25475434 http://dx.doi.org/10.2337/db14-0719

Ejemplares similares

Podocyte VEGF-A Knockdown Induces Diffuse Glomerulosclerosis in Diabetic and in eNOS Knockout Mice
por: Veron, Delma, et al.
Publicado: (2022)

Acute Podocyte Vascular Endothelial Growth Factor (VEGF-A) Knockdown Disrupts alpha(V)beta(3) Integrin Signaling in the Glomerulus
por: Veron, Delma, et al.
Publicado: (2012)

S-Nitrosylation of RhoGAP Myosin9A Is Altered in Advanced Diabetic Kidney Disease
por: Li, Qi, et al.
Publicado: (2021)

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
por: Gil, Natali, et al.
Publicado: (2012)

Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression
por: Fan, Ying, et al.
Publicado: (2019)

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy
por: Xiao, Li, et al.
Publicado: (2014)

Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice
por: Giacco, Ferdinando, et al.
Publicado: (2014)

Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy
por: Wang, Xin, et al.
Publicado: (2017)

Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy
por: Barutta, Federica, et al.
Publicado: (2011)

Enhanced Expression of Janus Kinase–Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy
por: Berthier, Celine C., et al.
Publicado: (2009)

Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model
por: Wang, Xiaoxin X., et al.
Publicado: (2010)

Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy
por: Guzman, Johanna, et al.
Publicado: (2014)

Cholesterol Accumulation in Podocytes: A Potential Novel Targetable Pathway in Diabetic Nephropathy
por: Tufro, Alda
Publicado: (2013)

Activation of Peroxisome Proliferator–Activated Receptor δ Inhibits Streptozotocin-Induced Diabetic Nephropathy Through Anti-Inflammatory Mechanisms in Mice
por: Matsushita, Yuichi, et al.
Publicado: (2011)

Resveratrol Improves Oxidative Stress and Protects Against Diabetic Nephropathy Through Normalization of Mn-SOD Dysfunction in AMPK/SIRT1-Independent Pathway
por: Kitada, Munehiro, et al.
Publicado: (2011)

Sulfasalazine Blocks the Development of Tactile Allodynia in Diabetic Rats
por: Berti-Mattera, Liliana N., et al.
Publicado: (2008)

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes
por: Soro-Paavonen, Aino, et al.
Publicado: (2008)

Variations in Risk of End-Stage Renal Disease and Risk of Mortality in an International Study of Patients With Type 1 Diabetes and Advanced Nephropathy
por: Skupien, Jan, et al.
Publicado: (2019)

Inflammation and Progressive Nephropathy in Type 1 Diabetes in the Diabetes Control and Complications Trial
por: Lin, Julie, et al.
Publicado: (2008)

Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing
por: Qu, Hua, et al.
Publicado: (2021)

Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes
por: Saulnier, Pierre-Jean, et al.
Publicado: (2016)

Relationship of Glycated Albumin to Blood Glucose and HbA(1c) Values and to Retinopathy, Nephropathy, and Cardiovascular Outcomes in the DCCT/EDIC Study
por: Nathan, David M., et al.
Publicado: (2014)

Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy
por: Rajesh, Mohanraj, et al.
Publicado: (2012)

Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse
por: Reiniger, Nina, et al.
Publicado: (2010)

Clinicopathological features of fast eGFR decliners among patients with diabetic nephropathy
por: Furuichi, Kengo, et al.
Publicado: (2020)

Role of Glyceraldehyde 3-Phosphate Dehydrogenase in the Development and Progression of Diabetic Retinopathy
por: Kanwar, Mamta, et al.
Publicado: (2009)

A 7-year-old boy with renal insufficiency and proteinuria after stem cell transplant for T-cell acute lymphoblastic leukemia
por: Goodwin, Julie E., et al.
Publicado: (2014)

Skin Advanced Glycation End Products Glucosepane and Methylglyoxal Hydroimidazolone Are Independently Associated With Long-term Microvascular Complication Progression of Type 1 Diabetes
por: Genuth, Saul, et al.
Publicado: (2015)

Improvements in the Life Expectancy of Type 1 Diabetes: The Pittsburgh Epidemiology of Diabetes Complications Study Cohort
por: Miller, Rachel G., et al.
Publicado: (2012)

New Diabetes Diagnostic Threshold of Hemoglobin A(1c) and the 3-Year Incidence of Retinopathy
por: Tsugawa, Yusuke, et al.
Publicado: (2012)

Urinary adiponectin as a new diagnostic index for chronic kidney disease due to diabetic nephropathy
por: Yamakado, Shinnosuke, et al.
Publicado: (2019)

Early-Outgrowth Bone Marrow Cells Attenuate Renal Injury and Dysfunction via an Antioxidant Effect in a Mouse Model of Type 2 Diabetes
por: Zhang, Yanling, et al.
Publicado: (2012)

Silence of TRIB3 Suppresses Atherosclerosis and Stabilizes Plaques in Diabetic ApoE(−/−)/LDL Receptor(−/−) Mice
por: Wang, Zhi-hao, et al.
Publicado: (2012)

Transcriptome Analysis of Human Diabetic Kidney Disease
por: Woroniecka, Karolina I., et al.
Publicado: (2011)

Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury
por: Zhou, Han, et al.
Publicado: (2017)

Total Soluble and Endogenous Secretory Receptor for Advanced Glycation End Products as Predictive Biomarkers of Coronary Heart Disease Risk in Patients With Type 2 Diabetes: An Analysis From the CARDS Trial
por: Colhoun, Helen M., et al.
Publicado: (2011)

Declining trends of diabetic nephropathy, retinopathy and neuropathy with improving diabetes care indicators in Japanese patients with type 2 and type 1 diabetes (JDDM 46)
por: Yokoyama, Hiroki, et al.
Publicado: (2018)

Genome-Wide Transcriptional Analysis of Differentially Expressed Genes in Diabetic, Healing Corneal Epithelial Cells: Hyperglycemia-Suppressed TGFβ3 Expression Contributes to the Delay of Epithelial Wound Healing in Diabetic Corneas
por: Bettahi, Ilham, et al.
Publicado: (2014)

Levels of Oxidized LDL and Advanced Glycation End Products–Modified LDL in Circulating Immune Complexes Are Strongly Associated With Increased Levels of Carotid Intima-Media Thickness and Its Progression in Type 1 Diabetes
por: Lopes-Virella, Maria F., et al.
Publicado: (2011)

Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration
por: Dinh, Thanh, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_04klf9v6merf9u5u76388b0mtf