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mLST8 Promotes mTOR-Mediated Tumor Progression

The activity of the mechanistic target of rapamycin (mTOR) is elevated in various types of human cancers, implicating a role in tumor progression. However, the molecular mechanisms underlying mTOR upregulation remain unclear. In this study, we found that the expression of mLST8, a required subunit o...

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Detalles Bibliográficos
Autores principales: Kakumoto, Kyoko, Ikeda, Jun-ichiro, Okada, Masato, Morii, Eiichi, Oneyama, Chitose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408021/
https://www.ncbi.nlm.nih.gov/pubmed/25906254
http://dx.doi.org/10.1371/journal.pone.0119015