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Analysis of Time to Event Outcomes in Randomized Controlled Trials by Generalized Additive Models

BACKGROUND: Randomized Controlled Trials almost invariably utilize the hazard ratio calculated with a Cox proportional hazard model as a treatment efficacy measure. Despite the widespread adoption of HRs, these provide a limited understanding of the treatment effect and may even provide a biased est...

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Detalles Bibliográficos
Autores principales:	Argyropoulos, Christos, Unruh, Mark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408032/ https://www.ncbi.nlm.nih.gov/pubmed/25906075 http://dx.doi.org/10.1371/journal.pone.0123784

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