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Delayed Recompression for Decompression Sickness: Retrospective Analysis

INTRODUCTION: Most cases of decompression sickness (DCS) occur soon after surfacing, with 98% within 24 hours. Recompression using hyperbaric chamber should be administrated as soon as feasible in order to decrease bubble size and avoid further tissue injury. Unfortunately, there may be a significan...

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Autores principales: Hadanny, Amir, Fishlev, Gregori, Bechor, Yair, Bergan, Jacob, Friedman, Mony, Maliar, Amit, Efrati, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408070/
https://www.ncbi.nlm.nih.gov/pubmed/25906396
http://dx.doi.org/10.1371/journal.pone.0124919
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author Hadanny, Amir
Fishlev, Gregori
Bechor, Yair
Bergan, Jacob
Friedman, Mony
Maliar, Amit
Efrati, Shai
author_facet Hadanny, Amir
Fishlev, Gregori
Bechor, Yair
Bergan, Jacob
Friedman, Mony
Maliar, Amit
Efrati, Shai
author_sort Hadanny, Amir
collection PubMed
description INTRODUCTION: Most cases of decompression sickness (DCS) occur soon after surfacing, with 98% within 24 hours. Recompression using hyperbaric chamber should be administrated as soon as feasible in order to decrease bubble size and avoid further tissue injury. Unfortunately, there may be a significant time delay from surfacing to recompression. The time beyond which hyperbaric treatment is non effective is unclear. The aims of the study were first to evaluate the effect of delayed hyperbaric treatment, initiated more than 48h after surfacing for DCS and second, to evaluate the different treatment protocols. METHODS: From January 2000 to February 2014, 76 divers had delayed hyperbaric treatment (≥48h) for DCS in the Sagol center for Hyperbaric medicine and Research, Assaf-Harofeh Medical Center, Israel. Data were collected from their medical records and compared to data of 128 patients treated earlier than 48h after surfacing at the same hyperbaric institute. RESULTS: There was no significant difference, as to any of the baseline characteristics, between the delayed and early treatment groups. With respect to treatment results, at the delayed treatment divers, complete recovery was achieved in 76% of the divers, partial recovery in 17.1% and no improvement in 6.6%. Similar results were achieved when treatment started early, where 78% of the divers had complete recovery, 15.6% partial recovery and 6.2% no recovery. Delayed hyperbaric treatment using US Navy Table 6 protocol trended toward a better clinical outcome yet not statistically significant (OR=2.786, CI95%[0.896-8.66], p=0.07) compared to standard hyperbaric oxygen therapy of 90 minutes at 2 ATA, irrespective of the symptoms severity at presentation. CONCLUSIONS: Late recompression for DCS, 48 hours or more after surfacing, has clinical value and when applied can achieve complete recovery in 76% of the divers. It seems that the preferred hyperbaric treatment protocol should be based on US Navy Table 6.
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spelling pubmed-44080702015-05-04 Delayed Recompression for Decompression Sickness: Retrospective Analysis Hadanny, Amir Fishlev, Gregori Bechor, Yair Bergan, Jacob Friedman, Mony Maliar, Amit Efrati, Shai PLoS One Research Article INTRODUCTION: Most cases of decompression sickness (DCS) occur soon after surfacing, with 98% within 24 hours. Recompression using hyperbaric chamber should be administrated as soon as feasible in order to decrease bubble size and avoid further tissue injury. Unfortunately, there may be a significant time delay from surfacing to recompression. The time beyond which hyperbaric treatment is non effective is unclear. The aims of the study were first to evaluate the effect of delayed hyperbaric treatment, initiated more than 48h after surfacing for DCS and second, to evaluate the different treatment protocols. METHODS: From January 2000 to February 2014, 76 divers had delayed hyperbaric treatment (≥48h) for DCS in the Sagol center for Hyperbaric medicine and Research, Assaf-Harofeh Medical Center, Israel. Data were collected from their medical records and compared to data of 128 patients treated earlier than 48h after surfacing at the same hyperbaric institute. RESULTS: There was no significant difference, as to any of the baseline characteristics, between the delayed and early treatment groups. With respect to treatment results, at the delayed treatment divers, complete recovery was achieved in 76% of the divers, partial recovery in 17.1% and no improvement in 6.6%. Similar results were achieved when treatment started early, where 78% of the divers had complete recovery, 15.6% partial recovery and 6.2% no recovery. Delayed hyperbaric treatment using US Navy Table 6 protocol trended toward a better clinical outcome yet not statistically significant (OR=2.786, CI95%[0.896-8.66], p=0.07) compared to standard hyperbaric oxygen therapy of 90 minutes at 2 ATA, irrespective of the symptoms severity at presentation. CONCLUSIONS: Late recompression for DCS, 48 hours or more after surfacing, has clinical value and when applied can achieve complete recovery in 76% of the divers. It seems that the preferred hyperbaric treatment protocol should be based on US Navy Table 6. Public Library of Science 2015-04-23 /pmc/articles/PMC4408070/ /pubmed/25906396 http://dx.doi.org/10.1371/journal.pone.0124919 Text en © 2015 Hadanny et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Hadanny, Amir
Fishlev, Gregori
Bechor, Yair
Bergan, Jacob
Friedman, Mony
Maliar, Amit
Efrati, Shai
Delayed Recompression for Decompression Sickness: Retrospective Analysis
title Delayed Recompression for Decompression Sickness: Retrospective Analysis
title_full Delayed Recompression for Decompression Sickness: Retrospective Analysis
title_fullStr Delayed Recompression for Decompression Sickness: Retrospective Analysis
title_full_unstemmed Delayed Recompression for Decompression Sickness: Retrospective Analysis
title_short Delayed Recompression for Decompression Sickness: Retrospective Analysis
title_sort delayed recompression for decompression sickness: retrospective analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408070/
https://www.ncbi.nlm.nih.gov/pubmed/25906396
http://dx.doi.org/10.1371/journal.pone.0124919
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