Cargando…
Bilateral synchronous carcinoma breast- a rare case presentation
INTRODUCTION: Bilateral Breast Carcinoma (BBC) is a rare entity with incidence of synchronous carcinoma being 2-5% of all breast malignancies, which is much less than metachronous carcinoma. Synchronicity/ metachronicity are usually associated with local and lymphatic spread and with blood–borne spr...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408308/ https://www.ncbi.nlm.nih.gov/pubmed/25932376 http://dx.doi.org/10.1186/s40064-015-0953-3 |
_version_ | 1782368036882219008 |
---|---|
author | Kappikeri, Vijay Kumar Shankarrao Kriplani, Akshay Mahesh |
author_facet | Kappikeri, Vijay Kumar Shankarrao Kriplani, Akshay Mahesh |
author_sort | Kappikeri, Vijay Kumar Shankarrao |
collection | PubMed |
description | INTRODUCTION: Bilateral Breast Carcinoma (BBC) is a rare entity with incidence of synchronous carcinoma being 2-5% of all breast malignancies, which is much less than metachronous carcinoma. Synchronicity/ metachronicity are usually associated with local and lymphatic spread and with blood–borne spread to lungs, bones and liver. Moreover BBC are mostly lobular carcinomas but we report a rare case of Infiltrating Ductal Carcinoma (IDC) as the primary carcinoma and Lobular Carcinoma as the secondary. CASE DESCRIPTION: 56 year old female who presented with a Stage IIIB fungating growth around 10x8cm in the lower inner, lower outer and upper outer quadrant of right breast since 6 months and a StageIIA 4x4cm tumour felt in the left breast in the upper inner and lower outer quadrant. Wedge biopsy of the right breast fungating mass showed Ductal Carcinoma and FNAC of the left breast lump suggested Lobular carcinoma which was confirmed on Histopathology after surgery. Patient was subjected to Hormonal therapy (Tab Tamoxifen), chemotherapy (Cyclophosphamide, 5 FU, and Doxorubicin) followed by Radiotherapy. Patient recovered well and shows no recurrence or signs of metastasis in the 8 months of follow up. DISCUSSION AND EVALUATION: Different histological subtypes with different grades of tumour in both breasts suggested two different synchronous primary tumours. Early detection of the contralateral tumour is of utmost importance emphasising the significance of breast self-examination. Screening tools like MRI have a greater sensitivity compared to Mammography. There are no clear treatment guidelines for bilateral breast cancer. Patients are often treated with bilateral mastectomy, with breast conservative surgery having unclear importance. CONCLUSION: Meticulous diagnosis and appropriate management help to improve the longitivity with an improved quality of life. |
format | Online Article Text |
id | pubmed-4408308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-44083082015-04-30 Bilateral synchronous carcinoma breast- a rare case presentation Kappikeri, Vijay Kumar Shankarrao Kriplani, Akshay Mahesh Springerplus Case Study INTRODUCTION: Bilateral Breast Carcinoma (BBC) is a rare entity with incidence of synchronous carcinoma being 2-5% of all breast malignancies, which is much less than metachronous carcinoma. Synchronicity/ metachronicity are usually associated with local and lymphatic spread and with blood–borne spread to lungs, bones and liver. Moreover BBC are mostly lobular carcinomas but we report a rare case of Infiltrating Ductal Carcinoma (IDC) as the primary carcinoma and Lobular Carcinoma as the secondary. CASE DESCRIPTION: 56 year old female who presented with a Stage IIIB fungating growth around 10x8cm in the lower inner, lower outer and upper outer quadrant of right breast since 6 months and a StageIIA 4x4cm tumour felt in the left breast in the upper inner and lower outer quadrant. Wedge biopsy of the right breast fungating mass showed Ductal Carcinoma and FNAC of the left breast lump suggested Lobular carcinoma which was confirmed on Histopathology after surgery. Patient was subjected to Hormonal therapy (Tab Tamoxifen), chemotherapy (Cyclophosphamide, 5 FU, and Doxorubicin) followed by Radiotherapy. Patient recovered well and shows no recurrence or signs of metastasis in the 8 months of follow up. DISCUSSION AND EVALUATION: Different histological subtypes with different grades of tumour in both breasts suggested two different synchronous primary tumours. Early detection of the contralateral tumour is of utmost importance emphasising the significance of breast self-examination. Screening tools like MRI have a greater sensitivity compared to Mammography. There are no clear treatment guidelines for bilateral breast cancer. Patients are often treated with bilateral mastectomy, with breast conservative surgery having unclear importance. CONCLUSION: Meticulous diagnosis and appropriate management help to improve the longitivity with an improved quality of life. Springer International Publishing 2015-04-22 /pmc/articles/PMC4408308/ /pubmed/25932376 http://dx.doi.org/10.1186/s40064-015-0953-3 Text en © Kappikeri and Kriplani; licensee Springer. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Case Study Kappikeri, Vijay Kumar Shankarrao Kriplani, Akshay Mahesh Bilateral synchronous carcinoma breast- a rare case presentation |
title | Bilateral synchronous carcinoma breast- a rare case presentation |
title_full | Bilateral synchronous carcinoma breast- a rare case presentation |
title_fullStr | Bilateral synchronous carcinoma breast- a rare case presentation |
title_full_unstemmed | Bilateral synchronous carcinoma breast- a rare case presentation |
title_short | Bilateral synchronous carcinoma breast- a rare case presentation |
title_sort | bilateral synchronous carcinoma breast- a rare case presentation |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408308/ https://www.ncbi.nlm.nih.gov/pubmed/25932376 http://dx.doi.org/10.1186/s40064-015-0953-3 |
work_keys_str_mv | AT kappikerivijaykumarshankarrao bilateralsynchronouscarcinomabreastararecasepresentation AT kriplaniakshaymahesh bilateralsynchronouscarcinomabreastararecasepresentation |