Cargando…

Promoter hypermethylation profiling of distant breast cancer metastases

Promoter hypermethylation of tumor suppressor genes seems to be an early event in breast carcinogenesis and is potentially reversible. This makes methylation a possible therapeutic target, a marker for treatment response and/or a prognostic factor. Methylation status of 40 tumor suppressor genes was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schrijver, Willemijne A. M. E., Jiwa, Laura S., van Diest, Paul J., Moelans, Cathy B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Preclinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408366/ https://www.ncbi.nlm.nih.gov/pubmed/25841351 http://dx.doi.org/10.1007/s10549-015-3362-y

Ejemplares similares

Frequent discordance in PD-1 and PD-L1 expression between primary breast tumors and their matched distant metastases
por: Manson, Quirine F., et al.
Publicado: (2018)

Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases
por: Jiwa, Laura S, et al.
Publicado: (2014)

Unravelling site-specific breast cancer metastasis: a microRNA expression profiling study
por: Schrijver, Willemijne A.M.E., et al.
Publicado: (2016)

Progressive APOBEC3B mRNA expression in distant breast cancer metastases
por: Sieuwerts, Anieta M., et al.
Publicado: (2017)

Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification
por: Kornegoor, Robert, et al.
Publicado: (2012)

Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer
por: Green, Andrew R., et al.
Publicado: (2016)

The prognostic effect of DDX3 upregulation in distant breast cancer metastases
por: Heerma van Voss, Marise R., et al.
Publicado: (2016)

Pregnancy-associated breast cancer: nationwide Dutch study confirms a discriminatory aggressive histopathologic profile
por: Suelmann, B. B. M., et al.
Publicado: (2021)

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome
por: Schrijver, Willemijne, et al.
Publicado: (2018)

Loss of steroid hormone receptors is common in malignant pleural and peritoneal effusions of breast cancer patients treated with endocrine therapy
por: Schrijver, Willemijne A.M.E., et al.
Publicado: (2017)

Promoter hypermethylation in male breast cancer: analysis by multiplex ligation-dependent probe amplification
por: Kornegoor, Robert, et al.
Publicado: (2012)

Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer
por: van der Groep, Petra, et al.
Publicado: (2007)

Genomic profiling using the UltraSEEK panel identifies discordancy between paired primary and breast cancer brain metastases and an association with brain metastasis-free survival
por: Giannoudis, Athina, et al.
Publicado: (2021)

DNA promoter hypermethylation in nipple fluid: a potential tool for early breast cancer detection
por: de Groot, Jolien S., et al.
Publicado: (2016)

CYP2C19*2 predicts substantial tamoxifen benefit in postmenopausal breast cancer patients randomized between adjuvant tamoxifen and no systemic treatment
por: Beelen, K., et al.
Publicado: (2013)

BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
por: Vos, Shoko, et al.
Publicado: (2017)

Hypermethylation of the Micro-RNA 145 Promoter Is the Key Regulator for NLRP3 Inflammasome-Induced Activation and Plaque Formation
por: Zhong, Wei, et al.
Publicado: (2018)

Loss of progesterone receptor is associated with distinct tyrosine kinase profiles in breast cancer
por: Tahiri, Andliena, et al.
Publicado: (2020)

Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study
por: Balmativola, D., et al.
Publicado: (2014)

Proteomic profile of KSR1-regulated signalling in response to genotoxic agents in breast cancer
por: Zhang, Hua, et al.
Publicado: (2015)

The spectrum of ATM missense variants and their contribution to contralateral breast cancer
por: Broeks, Annegien, et al.
Publicado: (2007)

Whole breast proton irradiation for maximal reduction of heart dose in breast cancer patients
por: Mast, Mirjam E., et al.
Publicado: (2014)

IMPARTER, Phase 1 of an intervention to improve patients’ understanding of gene expression profiling tests in breast cancer
por: Fallowfield, L. J., et al.
Publicado: (2022)

HPV-positive oropharyngeal squamous cell carcinoma is associated with TIMP3 and CADM1 promoter hypermethylation
por: van Kempen, Pauline M W, et al.
Publicado: (2014)

Receptor conversion in distant breast cancer metastases
por: Hoefnagel, Laurien DC, et al.
Publicado: (2010)

Genetic mutation profile of Chinese HER2-positive breast cancers and genetic predictors of responses to Neoadjuvant anti-HER2 therapy
por: Li, Kai, et al.
Publicado: (2020)

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4
por: Chen, Wenhu, et al.
Publicado: (2023)

Discordance between PAM50 intrinsic subtyping and immunohistochemistry in South African women with breast cancer
por: Dix-Peek, Thérèse, et al.
Publicado: (2023)

Molecular features of androgen-receptor low, estrogen receptor-negative breast cancers in the Carolina breast cancer study
por: Jinna, Nikita D., et al.
Publicado: (2023)

Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer
por: Noordermeer, Sylvie M., et al.
Publicado: (2012)

Enrichment of high-grade tumors in breast cancer gene expression studies
por: van Seijen, M., et al.
Publicado: (2017)

Breast cancer subtyping by immunohistochemistry and histological grade outperforms breast cancer intrinsic subtypes in predicting neoadjuvant chemotherapy response
por: Lips, E. H., et al.
Publicado: (2013)

PTEN promoter methylation predicts 10-year prognosis in hormone receptor-positive early breast cancer patients who received adjuvant tamoxifen endocrine therapy
por: Fan, Yu, et al.
Publicado: (2022)

Circulating tumour cell enumeration does not correlate with Miller–Payne grade in a cohort of breast cancer patients undergoing neoadjuvant chemotherapy
por: O’Toole, Sharon A., et al.
Publicado: (2020)

Stress vulnerability promotes an alcohol‐prone phenotype in a preclinical model of sustained depression
por: Riga, Danai, et al.
Publicado: (2018)

Retrospective analysis of metastatic behaviour of breast cancer subtypes
por: Savci-Heijink, C. Dilara, et al.
Publicado: (2015)

Under-ascertainment of breast cancer susceptibility gene carriers in a cohort of New Zealand female breast cancer patients
por: Lattimore, Vanessa, et al.
Publicado: (2020)

Breast cancer research and treatment reconstruction of unilateral breast structure using three-dimensional ultrasound imaging to assess breast neoplasm
por: Lu, Yuanyuan, et al.
Publicado: (2019)

A novel gene expression signature for bone metastasis in breast carcinomas
por: Savci-Heijink, C. Dilara, et al.
Publicado: (2016)

Quality assessment of estrogen receptor and progesterone receptor testing in breast cancer using a tissue microarray-based approach
por: Dekker, T. J. A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_95367o6p9493p1us1ehrnuna5e