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Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years

INTRODUCTION: Radical cystectomy in elderly patients is a controversial issue that has noticed an increase in importance overtime because of the lengthening average life span. Our objective was to determine if there were significant differences in the perioperative outcomes of patients over 70 years...

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Autores principales: Fontana, Pamela Portella, Gregorio, Sergio Alonso y, Rivas, Juan Gómez, Sánchez, Leslie Cuello, Ledo, Jesús Cisneros, Gómez, Ángel Tabernero, Sebastián, Jesús Díez, Barthel, Jesús Javier de la Peña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Urological Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408395/
https://www.ncbi.nlm.nih.gov/pubmed/25914834
http://dx.doi.org/10.5173/ceju.2015.01.498
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author Fontana, Pamela Portella
Gregorio, Sergio Alonso y
Rivas, Juan Gómez
Sánchez, Leslie Cuello
Ledo, Jesús Cisneros
Gómez, Ángel Tabernero
Sebastián, Jesús Díez
Barthel, Jesús Javier de la Peña
author_facet Fontana, Pamela Portella
Gregorio, Sergio Alonso y
Rivas, Juan Gómez
Sánchez, Leslie Cuello
Ledo, Jesús Cisneros
Gómez, Ángel Tabernero
Sebastián, Jesús Díez
Barthel, Jesús Javier de la Peña
author_sort Fontana, Pamela Portella
collection PubMed
description INTRODUCTION: Radical cystectomy in elderly patients is a controversial issue that has noticed an increase in importance overtime because of the lengthening average life span. Our objective was to determine if there were significant differences in the perioperative outcomes of patients over 70 years with bladder cancer treated with laparoscopic radical cystectomy (LRC) compared to those of younger patients. MATERIAL AND METHODS: We selected 180 patients who underwent LRC in our department in the period between 2005-2012. We divided them into 2 groups: 57% <70 years and 43% >70 years, and we compared the different parameters such as: comorbidities, intraoperative and post-operative complications, TNM stage and overall survival. RESULTS: The group <70 years had less comorbidities when compared with the group >70 years. Heterotopic urinary diversion was the diversion of choice in the elderly patients (97.4%). Paralytic ileus and the worsening of renal function were the only complications with statistical differences between the groups. Mean hospital length of stay was not significantly different between the groups. Younger and older patients had similar pathological staging : pT1 or less: 26,2 vs. 18.2%, pT2: 19.4 vs. 16.9%, pT3 38.8 vs. 37.7% and pT4 15.6 vs. 17.2%. Kaplan-Meier curves did not show significant differences in survival. CONCLUSIONS: Laparoscopic radical cystectomy in the elderly patient has similar rates of perioperative morbidity when compared with the younger patient and may be offered as a treatment option in selected elderly patients.
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spelling pubmed-44083952015-04-24 Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years Fontana, Pamela Portella Gregorio, Sergio Alonso y Rivas, Juan Gómez Sánchez, Leslie Cuello Ledo, Jesús Cisneros Gómez, Ángel Tabernero Sebastián, Jesús Díez Barthel, Jesús Javier de la Peña Cent European J Urol Original Paper INTRODUCTION: Radical cystectomy in elderly patients is a controversial issue that has noticed an increase in importance overtime because of the lengthening average life span. Our objective was to determine if there were significant differences in the perioperative outcomes of patients over 70 years with bladder cancer treated with laparoscopic radical cystectomy (LRC) compared to those of younger patients. MATERIAL AND METHODS: We selected 180 patients who underwent LRC in our department in the period between 2005-2012. We divided them into 2 groups: 57% <70 years and 43% >70 years, and we compared the different parameters such as: comorbidities, intraoperative and post-operative complications, TNM stage and overall survival. RESULTS: The group <70 years had less comorbidities when compared with the group >70 years. Heterotopic urinary diversion was the diversion of choice in the elderly patients (97.4%). Paralytic ileus and the worsening of renal function were the only complications with statistical differences between the groups. Mean hospital length of stay was not significantly different between the groups. Younger and older patients had similar pathological staging : pT1 or less: 26,2 vs. 18.2%, pT2: 19.4 vs. 16.9%, pT3 38.8 vs. 37.7% and pT4 15.6 vs. 17.2%. Kaplan-Meier curves did not show significant differences in survival. CONCLUSIONS: Laparoscopic radical cystectomy in the elderly patient has similar rates of perioperative morbidity when compared with the younger patient and may be offered as a treatment option in selected elderly patients. Polish Urological Association 2015-03-13 2015 /pmc/articles/PMC4408395/ /pubmed/25914834 http://dx.doi.org/10.5173/ceju.2015.01.498 Text en Copyright by Polish Urological Association http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Fontana, Pamela Portella
Gregorio, Sergio Alonso y
Rivas, Juan Gómez
Sánchez, Leslie Cuello
Ledo, Jesús Cisneros
Gómez, Ángel Tabernero
Sebastián, Jesús Díez
Barthel, Jesús Javier de la Peña
Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years
title Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years
title_full Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years
title_fullStr Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years
title_full_unstemmed Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years
title_short Perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years
title_sort perioperative and survival outcomes of laparoscopic radical cystectomy for bladder cancer in patients over 70 years
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408395/
https://www.ncbi.nlm.nih.gov/pubmed/25914834
http://dx.doi.org/10.5173/ceju.2015.01.498
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