Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors

RET can be activated in cis or trans by its co-receptors and ligands in vitro, but the physiological roles of trans signaling are unclear. Rapidly adapting (RA) mechanoreceptors in dorsal root ganglia (DRGs) express Ret and the co-receptor Gfrα2 and depend on Ret for survival and central projection...

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Detalles Bibliográficos
Autores principales: Fleming, Michael S, Vysochan, Anna, Paixão, Sόnia, Niu, Jingwen, Klein, Rüdiger, Savitt, Joseph M, Luo, Wenqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408446/
https://www.ncbi.nlm.nih.gov/pubmed/25838128
http://dx.doi.org/10.7554/eLife.06828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408446/
https://www.ncbi.nlm.nih.gov/pubmed/25838128
http://dx.doi.org/10.7554/eLife.06828

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