Cargando…
Primary hepatic lymphoma: A case report
Primary non-Hodgkin lymphoma of the liver is a very rare malignancy. In this case report, we describe a case of primary hepatic lymphoma (PHL) in a 60-year-old man who presented with lump and pain in the abdomen of 2 months’ duration. The patient had altered liver function, normal serum alfa fetopro...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408677/ https://www.ncbi.nlm.nih.gov/pubmed/25948944 http://dx.doi.org/10.4103/0970-9371.155232 |
_version_ | 1782368086727327744 |
---|---|
author | Patel, Trupti S. Malvania, Rujuta Shah, Majal C. Shah, Manoj J. Gami, Amisha G. |
author_facet | Patel, Trupti S. Malvania, Rujuta Shah, Majal C. Shah, Manoj J. Gami, Amisha G. |
author_sort | Patel, Trupti S. |
collection | PubMed |
description | Primary non-Hodgkin lymphoma of the liver is a very rare malignancy. In this case report, we describe a case of primary hepatic lymphoma (PHL) in a 60-year-old man who presented with lump and pain in the abdomen of 2 months’ duration. The patient had altered liver function, normal serum alfa fetoprotein level (AFP), normal hemogram and bone marrow. A computed tomography scan of the abdomen and pelvis showed an ill-defined hypodense mass with specks of calcification involving the liver, suggestive of primary malignant mass of liver. Diagnosis of PHL was established on the cytology smear and confirmed by immunohistochemistry on tissue biopsy. This case demonstrates that PHL should be considered in the differential diagnosis of space-occupying liver lesions in the presence of a normal level of AFP. Fine needle aspiration cytology is a faster and safer diagnostic modality even in such a rare case. The case has many unique features like negative serology for viruses, no type B symptom and normal lactate dehydrogenase level. |
format | Online Article Text |
id | pubmed-4408677 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-44086772015-05-06 Primary hepatic lymphoma: A case report Patel, Trupti S. Malvania, Rujuta Shah, Majal C. Shah, Manoj J. Gami, Amisha G. J Cytol Case Report Primary non-Hodgkin lymphoma of the liver is a very rare malignancy. In this case report, we describe a case of primary hepatic lymphoma (PHL) in a 60-year-old man who presented with lump and pain in the abdomen of 2 months’ duration. The patient had altered liver function, normal serum alfa fetoprotein level (AFP), normal hemogram and bone marrow. A computed tomography scan of the abdomen and pelvis showed an ill-defined hypodense mass with specks of calcification involving the liver, suggestive of primary malignant mass of liver. Diagnosis of PHL was established on the cytology smear and confirmed by immunohistochemistry on tissue biopsy. This case demonstrates that PHL should be considered in the differential diagnosis of space-occupying liver lesions in the presence of a normal level of AFP. Fine needle aspiration cytology is a faster and safer diagnostic modality even in such a rare case. The case has many unique features like negative serology for viruses, no type B symptom and normal lactate dehydrogenase level. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4408677/ /pubmed/25948944 http://dx.doi.org/10.4103/0970-9371.155232 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Patel, Trupti S. Malvania, Rujuta Shah, Majal C. Shah, Manoj J. Gami, Amisha G. Primary hepatic lymphoma: A case report |
title | Primary hepatic lymphoma: A case report |
title_full | Primary hepatic lymphoma: A case report |
title_fullStr | Primary hepatic lymphoma: A case report |
title_full_unstemmed | Primary hepatic lymphoma: A case report |
title_short | Primary hepatic lymphoma: A case report |
title_sort | primary hepatic lymphoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408677/ https://www.ncbi.nlm.nih.gov/pubmed/25948944 http://dx.doi.org/10.4103/0970-9371.155232 |
work_keys_str_mv | AT pateltruptis primaryhepaticlymphomaacasereport AT malvaniarujuta primaryhepaticlymphomaacasereport AT shahmajalc primaryhepaticlymphomaacasereport AT shahmanojj primaryhepaticlymphomaacasereport AT gamiamishag primaryhepaticlymphomaacasereport |