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Comparison of splice sites reveals that long noncoding RNAs are evolutionarily well conserved

Large-scale RNA sequencing has revealed a large number of long mRNA-like transcripts (lncRNAs) that do not code for proteins. The evolutionary history of these lncRNAs has been notoriously hard to study systematically due to their low level of sequence conservation that precludes comprehensive homol...

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Detalles Bibliográficos
Autores principales: Nitsche, Anne, Rose, Dominic, Fasold, Mario, Reiche, Kristin, Stadler, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408788/
https://www.ncbi.nlm.nih.gov/pubmed/25802408
http://dx.doi.org/10.1261/rna.046342.114

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