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Identification of elements in human long 3′ UTRs that inhibit nonsense-mediated decay

The nonsense-mediated mRNA decay (NMD) pathway serves an important role in gene expression by targeting aberrant mRNAs that have acquired premature termination codons (PTCs) as well as a subset of normally processed endogenous mRNAs. One determinant for the targeting of mRNAs by NMD is the occurrenc...

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Detalles Bibliográficos
Autores principales: Toma, Kalodiah G., Rebbapragada, Indrani, Durand, Sébastien, Lykke-Andersen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408796/
https://www.ncbi.nlm.nih.gov/pubmed/25805855
http://dx.doi.org/10.1261/rna.048637.114

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