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Spliceosome assembly in the absence of stable U4/U6 RNA pairing

The cycle of spliceosome assembly, intron excision, and spliceosome disassembly involves large-scale structural rearrangements of U6 snRNA that are functionally important. U6 enters the splicing pathway bound to the Prp24 protein, which chaperones annealing of U6 to U4 RNA to form a U4/U6 di-snRNP....

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Detalles Bibliográficos
Autores principales:	Burke, Jordan E., Butcher, Samuel E., Brow, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408799/ https://www.ncbi.nlm.nih.gov/pubmed/25762536 http://dx.doi.org/10.1261/rna.048421.114

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