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Role of transporters in the distribution of platinum-based drugs
Platinum derivatives used as chemotherapeutic drugs such as cisplatin and oxaliplatin have a potent antitumor activity. However, severe side effects such as nephro-, oto-, and neurotoxicity are associated with their use. Effects and side effects of platinum-based drugs are in part caused by their tr...
Autores principales: | Harrach, Saliha, Ciarimboli, Giuliano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408848/ https://www.ncbi.nlm.nih.gov/pubmed/25964760 http://dx.doi.org/10.3389/fphar.2015.00085 |
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