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Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital
BACKGROUND: Status epilepticus (SE) is a serious neurological condition and has high a mortality rate. Data on importance of factors associated with poor outcomes in Asian or Thai populations are limited. METHODS: Adult patients diagnosed as SE at Khon Kaen Hospital, Thailand from October 1, 2010 to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408942/ https://www.ncbi.nlm.nih.gov/pubmed/25945053 http://dx.doi.org/10.2147/NDT.S76193 |
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author | Chiewthanakul, Piyawan Noppaklao, Parinya Sawanyawisuth, Kittisak Tiamkao, Somsak |
author_facet | Chiewthanakul, Piyawan Noppaklao, Parinya Sawanyawisuth, Kittisak Tiamkao, Somsak |
author_sort | Chiewthanakul, Piyawan |
collection | PubMed |
description | BACKGROUND: Status epilepticus (SE) is a serious neurological condition and has high a mortality rate. Data on importance of factors associated with poor outcomes in Asian or Thai populations are limited. METHODS: Adult patients diagnosed as SE at Khon Kaen Hospital, Thailand from October 1, 2010 to September 30, 2012 were enrolled. Patients were categorized as good or poor outcomes at discharge. Good outcomes were defined by improvement at discharge and absence of neurological deficits, while poor outcomes were defined by: not being improved at discharge; being discharged against advice; death; or presence of a neurological deficit. Clinical factors were compared between both groups. RESULTS: During the study period, there were 211 patients diagnosed as SE. Of those, 130 patients were male (61.61%). The mean age of all patients was 53.28 years. Acute stroke was the most common cause of SE in 33 patients (15.64%). At discharge, there were 91 patients (43.13%) who had poor outcomes. Only initial plasma glucose levels were significantly associated with poor outcomes with an adjusted odds ratio of 1.012 (95% confidence interval of 1.003 and 1.021). CONCLUSION: Initial plasma glucose is associated with poor discharge status in patients with SE. |
format | Online Article Text |
id | pubmed-4408942 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-44089422015-05-05 Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital Chiewthanakul, Piyawan Noppaklao, Parinya Sawanyawisuth, Kittisak Tiamkao, Somsak Neuropsychiatr Dis Treat Original Research BACKGROUND: Status epilepticus (SE) is a serious neurological condition and has high a mortality rate. Data on importance of factors associated with poor outcomes in Asian or Thai populations are limited. METHODS: Adult patients diagnosed as SE at Khon Kaen Hospital, Thailand from October 1, 2010 to September 30, 2012 were enrolled. Patients were categorized as good or poor outcomes at discharge. Good outcomes were defined by improvement at discharge and absence of neurological deficits, while poor outcomes were defined by: not being improved at discharge; being discharged against advice; death; or presence of a neurological deficit. Clinical factors were compared between both groups. RESULTS: During the study period, there were 211 patients diagnosed as SE. Of those, 130 patients were male (61.61%). The mean age of all patients was 53.28 years. Acute stroke was the most common cause of SE in 33 patients (15.64%). At discharge, there were 91 patients (43.13%) who had poor outcomes. Only initial plasma glucose levels were significantly associated with poor outcomes with an adjusted odds ratio of 1.012 (95% confidence interval of 1.003 and 1.021). CONCLUSION: Initial plasma glucose is associated with poor discharge status in patients with SE. Dove Medical Press 2015-04-20 /pmc/articles/PMC4408942/ /pubmed/25945053 http://dx.doi.org/10.2147/NDT.S76193 Text en © 2015 Chiewthanakul et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Chiewthanakul, Piyawan Noppaklao, Parinya Sawanyawisuth, Kittisak Tiamkao, Somsak Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital |
title | Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital |
title_full | Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital |
title_fullStr | Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital |
title_full_unstemmed | Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital |
title_short | Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital |
title_sort | factors associated with poor discharge status in patients with status epilepticus at khon kaen hospital |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408942/ https://www.ncbi.nlm.nih.gov/pubmed/25945053 http://dx.doi.org/10.2147/NDT.S76193 |
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