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Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital

BACKGROUND: Status epilepticus (SE) is a serious neurological condition and has high a mortality rate. Data on importance of factors associated with poor outcomes in Asian or Thai populations are limited. METHODS: Adult patients diagnosed as SE at Khon Kaen Hospital, Thailand from October 1, 2010 to...

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Autores principales: Chiewthanakul, Piyawan, Noppaklao, Parinya, Sawanyawisuth, Kittisak, Tiamkao, Somsak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408942/
https://www.ncbi.nlm.nih.gov/pubmed/25945053
http://dx.doi.org/10.2147/NDT.S76193
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author Chiewthanakul, Piyawan
Noppaklao, Parinya
Sawanyawisuth, Kittisak
Tiamkao, Somsak
author_facet Chiewthanakul, Piyawan
Noppaklao, Parinya
Sawanyawisuth, Kittisak
Tiamkao, Somsak
author_sort Chiewthanakul, Piyawan
collection PubMed
description BACKGROUND: Status epilepticus (SE) is a serious neurological condition and has high a mortality rate. Data on importance of factors associated with poor outcomes in Asian or Thai populations are limited. METHODS: Adult patients diagnosed as SE at Khon Kaen Hospital, Thailand from October 1, 2010 to September 30, 2012 were enrolled. Patients were categorized as good or poor outcomes at discharge. Good outcomes were defined by improvement at discharge and absence of neurological deficits, while poor outcomes were defined by: not being improved at discharge; being discharged against advice; death; or presence of a neurological deficit. Clinical factors were compared between both groups. RESULTS: During the study period, there were 211 patients diagnosed as SE. Of those, 130 patients were male (61.61%). The mean age of all patients was 53.28 years. Acute stroke was the most common cause of SE in 33 patients (15.64%). At discharge, there were 91 patients (43.13%) who had poor outcomes. Only initial plasma glucose levels were significantly associated with poor outcomes with an adjusted odds ratio of 1.012 (95% confidence interval of 1.003 and 1.021). CONCLUSION: Initial plasma glucose is associated with poor discharge status in patients with SE.
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spelling pubmed-44089422015-05-05 Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital Chiewthanakul, Piyawan Noppaklao, Parinya Sawanyawisuth, Kittisak Tiamkao, Somsak Neuropsychiatr Dis Treat Original Research BACKGROUND: Status epilepticus (SE) is a serious neurological condition and has high a mortality rate. Data on importance of factors associated with poor outcomes in Asian or Thai populations are limited. METHODS: Adult patients diagnosed as SE at Khon Kaen Hospital, Thailand from October 1, 2010 to September 30, 2012 were enrolled. Patients were categorized as good or poor outcomes at discharge. Good outcomes were defined by improvement at discharge and absence of neurological deficits, while poor outcomes were defined by: not being improved at discharge; being discharged against advice; death; or presence of a neurological deficit. Clinical factors were compared between both groups. RESULTS: During the study period, there were 211 patients diagnosed as SE. Of those, 130 patients were male (61.61%). The mean age of all patients was 53.28 years. Acute stroke was the most common cause of SE in 33 patients (15.64%). At discharge, there were 91 patients (43.13%) who had poor outcomes. Only initial plasma glucose levels were significantly associated with poor outcomes with an adjusted odds ratio of 1.012 (95% confidence interval of 1.003 and 1.021). CONCLUSION: Initial plasma glucose is associated with poor discharge status in patients with SE. Dove Medical Press 2015-04-20 /pmc/articles/PMC4408942/ /pubmed/25945053 http://dx.doi.org/10.2147/NDT.S76193 Text en © 2015 Chiewthanakul et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Chiewthanakul, Piyawan
Noppaklao, Parinya
Sawanyawisuth, Kittisak
Tiamkao, Somsak
Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital
title Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital
title_full Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital
title_fullStr Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital
title_full_unstemmed Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital
title_short Factors associated with poor discharge status in patients with status epilepticus at Khon Kaen Hospital
title_sort factors associated with poor discharge status in patients with status epilepticus at khon kaen hospital
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408942/
https://www.ncbi.nlm.nih.gov/pubmed/25945053
http://dx.doi.org/10.2147/NDT.S76193
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