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Establishment of a New Quality Control and Vaccine Safety Test for Influenza Vaccines and Adjuvants Using Gene Expression Profiling
We have previously identified 17 biomarker genes which were upregulated by whole virion influenza vaccines, and reported that gene expression profiles of these biomarker genes had a good correlation with conventional animal safety tests checking body weight and leukocyte counts. In this study, we ha...
Autores principales: | Momose, Haruka, Mizukami, Takuo, Kuramitsu, Madoka, Takizawa, Kazuya, Masumi, Atsuko, Araki, Kumiko, Furuhata, Keiko, Yamaguchi, Kazunari, Hamaguchi, Isao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409070/ https://www.ncbi.nlm.nih.gov/pubmed/25909814 http://dx.doi.org/10.1371/journal.pone.0124392 |
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