Clostridium perfringens Alpha-Toxin Induces Gm1a Clustering and Trka Phosphorylation in the Host Cell Membrane

Clostridium perfringens alpha-toxin elicits various immune responses such as the release of cytokines, chemokines, and superoxide via the GM1a/TrkA complex. Alpha-toxin possesses phospholipase C (PLC) hydrolytic activity that contributes to signal transduction in the pathogenesis of gas gangrene. Li...

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Detalles Bibliográficos
Autores principales: Takagishi, Teruhisa, Oda, Masataka, Kabura, Michiko, Kurosawa, Mie, Tominaga, Kaori, Urano, Shiori, Ueda, Yoshibumi, Kobayashi, Keiko, Kobayashi, Toshihide, Sakurai, Jun, Terao, Yutaka, Nagahama, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409118/
https://www.ncbi.nlm.nih.gov/pubmed/25910247
http://dx.doi.org/10.1371/journal.pone.0120497

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