Cargando…

High Frequency of Resistance, Lack of Clinical Benefit, and Poor Outcomes in Capreomycin Treated South African Patients with Extensively Drug-Resistant Tuberculosis

BACKGROUND: There are limited data about the epidemiology and treatment-related outcomes associated with capreomycin resistance in patients with XDR-TB. Capreomycin achieves high serum concentrations relative to MIC but whether capreomycin has therapeutic benefit despite microbiological resistance r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pietersen, Elize, Peter, Jonny, Streicher, Elizabeth, Sirgel, Frik, Rockwood, Neesha, Mastrapa, Barbara, Te Riele, Julian, Davids, Malika, van Helden, Paul, Warren, Robin, Dheda, Keertan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409172/ https://www.ncbi.nlm.nih.gov/pubmed/25909847 http://dx.doi.org/10.1371/journal.pone.0123655

Ejemplares similares

The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates
por: Tomasicchio, Michele, et al.
Publicado: (2016)

What is the Cost of Diagnosis and Management of Drug Resistant Tuberculosis in South Africa?
por: Pooran, Anil, et al.
Publicado: (2013)

Low Frequency of Acquired Isoniazid and Rifampicin Resistance in Rifampicin-Susceptible Pulmonary Tuberculosis in a Setting of High HIV-1 Infection and Tuberculosis Coprevalence
por: Rockwood, Neesha, et al.
Publicado: (2017)

Drug-Associated Adverse Events and Their Relationship with Outcomes in Patients Receiving Treatment for Extensively Drug-Resistant Tuberculosis in South Africa
por: Shean, Karen, et al.
Publicado: (2013)

High mortality among patients hospitalized for drug‐resistant tuberculosis with acquired second‐line drug resistance and high HIV prevalence
por: Anderson, Kim, et al.
Publicado: (2022)

Correction: Drug-Associated Adverse Events and Their Relationship with Outcomes in Patients Receiving Treatment for Extensively Drug-Resistant Tuberculosis in South Africa
por: Shean, Karen, et al.
Publicado: (2013)

Latent Tuberculosis Infection–associated Immunodiagnostic Test Responses as Biomarkers of Incipient Tuberculosis: Fruitful or Futile?
por: Dheda, Keertan, et al.
Publicado: (2020)

Variation in missed doses and reasons for discontinuation of anti-tuberculosis drugs during hospital treatment for drug-resistant tuberculosis in South Africa
por: Pietersen, Elize, et al.
Publicado: (2023)

Transmission, distribution and drug resistance-conferring mutations of extensively drug-resistant tuberculosis in the Western Cape Province, South Africa
por: Oostvogels, Selien, et al.
Publicado: (2022)

GenoType(®) MTBDRsl assay for resistance to second‐line anti‐tuberculosis drugs
por: Theron, Grant, et al.
Publicado: (2016)

Capreomycin-induced optic neuritis in a case of multidrug resistant pulmonary tuberculosis
por: Magazine, Rahul, et al.
Publicado: (2010)

Emergence and Spread of Extensively and Totally Drug-Resistant Tuberculosis, South Africa
por: Klopper, Marisa, et al.
Publicado: (2013)

Sleepiness Score-Specific Outcomes of a Novel Tongue Repositioning Procedure for the Treatment of Continuous Positive Airway Pressure-Resistant Obstructive Sleep Apnea
por: Hendricks, Rushdi, et al.
Publicado: (2019)

The Frequency and Effect of Granulocytic Myeloid-Derived Suppressor Cells on Mycobacterial Survival in Patients With Tuberculosis: A Preliminary Report
por: Davids, Malika, et al.
Publicado: (2021)

Molecular characterization of amikacin, kanamycin and capreomycin resistance in M/XDR-TB strains isolated in Thailand
por: Sowajassatakul, Angkanang, et al.
Publicado: (2014)

The diagnostic accuracy of the GenoType® Mtbdrsl assay for the detection of resistance to second-line anti-tuberculosis drugs
por: Theron, Grant, et al.
Publicado: (2014)

Capreomycin is active against non-replicating M. tuberculosis
por: Heifets, Leonid, et al.
Publicado: (2005)

Evaluation of Genetic Mutations Associated with Mycobacterium tuberculosis Resistance to Amikacin, Kanamycin and Capreomycin: A Systematic Review
por: Georghiou, Sophia B., et al.
Publicado: (2012)

A Survey on Use of Rapid Tests and Tuberculosis Diagnostic Practices by Primary Health Care Providers in South Africa: Implications for the Development of New Point-of-Care Tests
por: Davids, Malika, et al.
Publicado: (2015)

Making HIV testing work at the point of care in South Africa: a qualitative study of diagnostic practices
por: Engel, Nora, et al.
Publicado: (2017)

Co-Delivery of D-LAK Antimicrobial Peptide and Capreomycin as Inhaled Powder Formulation to Combat Drug-Resistant Tuberculosis
por: Shao, Zitong, et al.
Publicado: (2023)

Evaluation of Susceptibility of the Human Pathogen Helicobacter pylori to the Antibiotic Capreomycin
por: Sukati, Suriyan, et al.
Publicado: (2022)

What is new in the WHO consolidated guidelines on drug-resistant tuberculosis treatment?
por: Sharma, Surendra K., et al.
Publicado: (2019)

Assessment of Amikacin- and Capreomycin-Related Adverse Drug Reactions in Patients with Multidrug-Resistant Tuberculosis and Exploring the Role of Genetic Factors
por: Freimane, Lauma, et al.
Publicado: (2023)

Emergence of Increased Resistance and Extensively Drug-Resistant Tuberculosis Despite Treatment Adherence, South Africa
por: Calver, Alistair D., et al.
Publicado: (2010)

The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
por: Stanley, Robin E., et al.
Publicado: (2010)

Spray-Dried Powder Formulation of Capreomycin Designed for Inhaled Tuberculosis Therapy
por: Shao, Zitong, et al.
Publicado: (2021)

Rapid Diagnosis of Drug Resistance to Fluoroquinolones, Amikacin, Capreomycin, Kanamycin and Ethambutol Using Genotype MTBDRsl Assay: A Meta-Analysis
por: Feng, Yan, et al.
Publicado: (2013)

Outcomes of patients undergoing lung resection for drug-resistant TB and the prognostic significance of pre-operative positron emission tomography/computed tomography (PET/CT) in predicting treatment failure
por: Calligaro, Gregory L., et al.
Publicado: (2022)

Comparison of treatment outcome definitions in drug-resistant tuberculosis patients with high incidence of acquired second-line drug resistance
por: Anderson, K, et al.
Publicado: (2022)

Programmatically Selected Multidrug-Resistant Strains Drive the Emergence of Extensively Drug-Resistant Tuberculosis in South Africa
por: Müller, Borna, et al.
Publicado: (2013)

The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis–Specific Host Immunity Through the Glucocorticoid Receptor
por: Tomasicchio, Michele, et al.
Publicado: (2019)

HIV associated Lymphocytic Interstitial Pneumonia: a clinical, histological and radiographic study from an HIV endemic resource-poor setting
por: van Zyl-Smit, Richard N, et al.
Publicado: (2015)

Risk Factors for Acquired Rifamycin and Isoniazid Resistance: A Systematic Review and Meta-Analysis
por: Rockwood, Neesha, et al.
Publicado: (2015)

Diagnosis of COVID-19: Considerations, Controversies and Challenges in South Africa
por: Dheda, Keertan, et al.
Publicado: (2020)

Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing
por: Dheda, Keertan, et al.
Publicado: (2019)

Concentration-Dependent Antagonism and Culture Conversion in Pulmonary Tuberculosis
por: Rockwood, Neesha, et al.
Publicado: (2017)

Vulnerability as a Precondition for Resistance and Agency: Young Women in a Regional Community
por: te Riele, Kitty, et al.
Publicado: (2021)

Xpert(®) MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance
por: Kohli, Mikashmi, et al.
Publicado: (2018)

Rifampin- or Capreomycin-Induced Remodeling of the Mycobacterium smegmatis Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic Antimicrobial Peptides
por: Man, DeDe Kwun-Wai, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_109o2tlqrro46rijk6up8jnj64