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Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage
Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane components in vivo, as well as by a proteomics analysis of exudates collected in tissue injected with these enzymes. Immun...
Autores principales: | Herrera, Cristina, Escalante, Teresa, Voisin, Mathieu-Benoit, Rucavado, Alexandra, Morazán, Diego, Macêdo, Jéssica Kele A., Calvete, Juan J., Sanz, Libia, Nourshargh, Sussan, Gutiérrez, José María, Fox, Jay W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409213/ https://www.ncbi.nlm.nih.gov/pubmed/25909592 http://dx.doi.org/10.1371/journal.pntd.0003731 |
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