Cargando…

Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Atherosclerosis stems from imbalances in lipid metabolism and leads to maladaptive inflammatory responses. The AMP-activated protein kinase (Ampk) is a highly conserved serine/threonine kinase that regulates many aspects of lipid and energy metabolism, although its specific role in controlling macro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fullerton, Morgan D., Ford, Rebecca J., McGregor, Chelsea P., LeBlond, Nicholas D., Snider, Shayne A., Stypa, Stephanie A., Day, Emily A., Lhoták, Šárka, Schertzer, Jonathan D., Austin, Richard C., Kemp, Bruce E., Steinberg, Gregory R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409279/ https://www.ncbi.nlm.nih.gov/pubmed/25773887 http://dx.doi.org/10.1194/jlr.M058875

Ejemplares similares

Salsalate reduces atherosclerosis through AMPKβ1 in mice
por: Day, Emily A., et al.
Publicado: (2021)

Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis
por: LeBlond, Nicholas D., et al.
Publicado: (2020)

Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice
por: LeBlond, Nicholas D., et al.
Publicado: (2020)

Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis
por: Basseri, Sana, et al.
Publicado: (2013)

Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis
por: Lee, Man K.S., et al.
Publicado: (2022)

Macrophage AMPK β1 activation by PF-06409577 reduces the inflammatory response, cholesterol synthesis, and atherosclerosis in mice
por: Day, Emily A., et al.
Publicado: (2023)

SIRT1 Takes a Backseat to AMPK in the Regulation of Insulin Sensitivity by Resveratrol
por: Fullerton, Morgan D., et al.
Publicado: (2010)

Skeletal muscle AMPK is essential for the maintenance of FNDC5 expression
por: Lally, James S V, et al.
Publicado: (2015)

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin–sensitizing effects of metformin
por: Fullerton, Morgan D., et al.
Publicado: (2013)

The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids
por: Desjardins, Eric M., et al.
Publicado: (2022)

Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway
por: Wang, Xin, et al.
Publicado: (2020)

Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK
por: Hunter, Roger W., et al.
Publicado: (2014)

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
por: Pinkosky, Stephen L., et al.
Publicado: (2016)

Using 1-2-3 /
por: LeBlond, Geoffrey T.
Publicado: (1985)

Cómo usar Lotus 1-2-3 : versión 2.01, incluye avance de las versiones 2.2 y 3
por: LeBlond, Geoffrey T.
Publicado: (1990)

Cómo usar lotus 1-2-3 : La herramienta para gerenciar la productividad
por: LeBlond, Geoffrey T.
Publicado: (1990)

Cómo usar Lotus 1-2-3 : la herramienta para gerenciar la productividad
por: LeBlond, Geoffrey T.
Publicado: (1989)

Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis
por: Das, Akash, et al.
Publicado: (2014)

ASP.NET cookbook
por: LeBlond, Geoffrey T, et al.
Publicado: (2004)

ASP.NET 2.0 cookbook
por: Kittel, Michael A, et al.
Publicado: (2006)

Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging
por: Crane, Justin D, et al.
Publicado: (2015)

Myeloid PTP1B deficiency protects against atherosclerosis by improving cholesterol homeostasis through an AMPK-dependent mechanism
por: Oliver, Helk, et al.
Publicado: (2023)

DeGowin, examen diagnóstico /
por: LeBlond, Richard F.
Publicado: (2010)

A Diacylglycerol Kinase Inhibitor, R-59-022, Blocks Filovirus Internalization in Host Cells
por: Stewart, Corina M., et al.
Publicado: (2019)

Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages
por: Smith, Tyler K. T., et al.
Publicado: (2019)

Spatial Distribution of the Pathways of Cholesterol Homeostasis in Human Retina
por: Zheng, Wenchao, et al.
Publicado: (2012)

ABCD1 Transporter Deficiency Results in Altered Cholesterol Homeostasis
por: Buda, Agnieszka, et al.
Publicado: (2023)

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models
por: Esquejo, Ryan M., et al.
Publicado: (2018)

Hypothalamic AMPK as a Regulator of Energy Homeostasis
por: Huynh, My Khanh Q., et al.
Publicado: (2016)

Epigenetic regulation of cholesterol homeostasis
por: Meaney, Steve
Publicado: (2014)

Cholesterol metabolism and homeostasis in the brain
por: Zhang, Juan, et al.
Publicado: (2015)

SUMOylation in the control of cholesterol homeostasis
por: Talamillo, Ana, et al.
Publicado: (2020)

Lactate Shuttles in Neuroenergetics—Homeostasis, Allostasis and Beyond
por: Mason, Shayne
Publicado: (2017)

Inhibition of Adenosine Monophosphate–Activated Protein Kinase–3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance
por: Loh, Kim, et al.
Publicado: (2018)

Intracellular and Plasma Membrane Events in Cholesterol Transport and Homeostasis
por: Litvinov, Dmitry Y., et al.
Publicado: (2018)

From Dietary Cholesterol to Blood Cholesterol, Physiological Lipid Fluxes, and Cholesterol Homeostasis
por: Stellaard, Frans
Publicado: (2022)

Do viruses subvert cholesterol homeostasis to induce host cubic membranes?
por: Deng, Yuru, et al.
Publicado: (2010)

Intravenous Sodium Salicylate
por: Vasavada, D. M.
Publicado: (1923)

Solvent for Salicylic Acid
por: Edmiston, D. W.
Publicado: (1877)

Salicin, Salicylic Acid and the Salicylates
Publicado: (1878)

Cannot write session to /tmp/vufind_sessions/sess_mrffp22r0j6m1mhmi8t8gs01iq