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Multiplex Eukaryotic Transcription (In)activation: Timing, Bursting and Cycling of a Ratchet Clock Mechanism
Activation of eukaryotic transcription is an intricate process that relies on a multitude of regulatory proteins forming complexes on chromatin. Chromatin modifications appear to play a guiding role in protein-complex assembly on chromatin. Together, these processes give rise to stochastic, often bu...
Autores principales: | Rybakova, Katja N., Bruggeman, Frank J., Tomaszewska, Aleksandra, Moné, Martijn J., Carlberg, Carsten, Westerhoff, Hans V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409292/ https://www.ncbi.nlm.nih.gov/pubmed/25909187 http://dx.doi.org/10.1371/journal.pcbi.1004236 |
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