Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs

In a survey of 20 knockout mouse lines designed to examine the biological functions of large intergenic non-coding RNAs (lincRNAs), we have found a variety of phenotypes, ranging from perinatal lethality to defects associated with premature aging and morphological and functional abnormalities in the...

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Detalles Bibliográficos
Autores principales: Lai, Ka-Man Venus, Gong, Guochun, Atanasio, Amanda, Rojas, José, Quispe, Joseph, Posca, Julita, White, Derek, Huang, Mei, Fedorova, Daria, Grant, Craig, Miloscio, Lawrence, Droguett, Gustavo, Poueymirou, William T., Auerbach, Wojtek, Yancopoulos, George D., Frendewey, David, Rinn, John, Valenzuela, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409293/
https://www.ncbi.nlm.nih.gov/pubmed/25909911
http://dx.doi.org/10.1371/journal.pone.0125522

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