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Early Systemic Microvascular Damage in Pigs with Atherogenic Diabetes Mellitus Coincides with Renal Angiopoietin Dysbalance
BACKGROUND: Diabetes mellitus (DM) is associated with a range of microvascular complications including diabetic nephropathy (DN). Microvascular abnormalities in the kidneys are common histopathologic findings in DN, which represent one manifestation of ongoing systemic microvascular damage. Recently...
Autores principales: | Khairoun, Meriem, van den Heuvel, Mieke, van den Berg, Bernard M., Sorop, Oana, de Boer, Rients, van Ditzhuijzen, Nienke S., Bajema, Ingeborg M., Baelde, Hans J., Zandbergen, Malu, Duncker, Dirk J., Rabelink, Ton J., Reinders, Marlies E. J., van der Giessen, Wim J., Rotmans, Joris I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409307/ https://www.ncbi.nlm.nih.gov/pubmed/25909188 http://dx.doi.org/10.1371/journal.pone.0121555 |
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