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MicroRNA let-7c Inhibits Cell Proliferation and Induces Cell Cycle Arrest by Targeting CDC25A in Human Hepatocellular Carcinoma

Down-regulation of the microRNA let-7c plays an important role in the pathogenesis of human hepatocellular carcinoma (HCC). The aim of the present study was to determine whether the cell cycle regulator CDC25A is involved in the antitumor effect of let-7c in HCC. The expression levels of let-7c in H...

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Detalles Bibliográficos
Autores principales: Zhu, Xiuming, Wu, Lingjiao, Yao, Jian, Jiang, Han, Wang, Qiangfeng, Yang, Zhijian, Wu, Fusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409336/
https://www.ncbi.nlm.nih.gov/pubmed/25909324
http://dx.doi.org/10.1371/journal.pone.0124266