Plasma TNF-α and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna—A Randomized, Cross-Over Clinical Study

PURPOSE: Chemotherapy-induced cognitive impairment (CICI) is a common sequelae of cancer therapy. Recent preclinical observations have suggested that CICI can be mediated by chemotherapy-induced plasma protein oxidation, which triggers TNF-α mediated CNS damage. This study evaluated sodium-2-mercapt...

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Detalles Bibliográficos
Autores principales: Hayslip, John, Dressler, Emily V., Weiss, Heidi, Taylor, Tammy J., Chambers, Mara, Noel, Teresa, Miriyala, Sumitra, Keeney, Jeriel T. R., Ren, Xiaojia, Sultana, Rukhsana, Vore, Mary, Butterfield, D. Allan, St Clair, Daret, Moscow, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409356/
https://www.ncbi.nlm.nih.gov/pubmed/25909710
http://dx.doi.org/10.1371/journal.pone.0124988

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