Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFκB and ERK

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by abnormal autoreactivity in B cells. Lymphocytes and their soluble mediators contribute to the disease pathogenesis. We recently demonstrated that infecting lupus mice with malaria confers protection against lupus...

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Detalles Bibliográficos
Autores principales: Badr, Gamal, Sayed, Ayat, Abdel-Maksoud, Mostafa A., Mohamed, Amany O., El-Amir, Azza, Abdel-Ghaffar, Fathy A., Al-Quraishy, Saleh, Mahmoud, Mohamed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409368/
https://www.ncbi.nlm.nih.gov/pubmed/25909640
http://dx.doi.org/10.1371/journal.pone.0125340

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