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Gene Electrotransfer of Plasmid with Tissue Specific Promoter Encoding shRNA against Endoglin Exerts Antitumor Efficacy against Murine TS/A Tumors by Vascular Targeted Effects

Vascular targeted therapies, targeting specific endothelial cell markers, are promising approaches for the treatment of cancer. One of the targets is endoglin, transforming growth factor-β (TGF-β) co-receptor, which mediates proliferation, differentiation and migration of endothelial cells forming n...

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Detalles Bibliográficos
Autores principales: Stimac, Monika, Dolinsek, Tanja, Lampreht, Ursa, Cemazar, Maja, Sersa, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409373/
https://www.ncbi.nlm.nih.gov/pubmed/25909447
http://dx.doi.org/10.1371/journal.pone.0124913