Genetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus’s Role in Virulence

Invasive aspergillosis (IA) due to Aspergillus fumigatus is a major cause of mortality in immunocompromised patients. The discovery of highly fertile strains of A. fumigatus opened the possibility to merge classical and contemporary genetics to address key questions about this pathogen. The merger i...

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Detalles Bibliográficos
Autores principales: Losada, Liliana, Sugui, Janyce A., Eckhaus, Michael A., Chang, Yun C., Mounaud, Stephanie, Figat, Abigail, Joardar, Vinita, Pakala, Suman B., Pakala, Suchitra, Venepally, Pratap, Fedorova, Natalie, Nierman, William C., Kwon-Chung, Kyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409388/
https://www.ncbi.nlm.nih.gov/pubmed/25909486
http://dx.doi.org/10.1371/journal.ppat.1004834

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