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The Novel Analogue of Hirsutine as an Anti-Hypertension and Vasodilatary Agent Both In Vitro and In Vivo

In this paper, an analogue of hirsutine (compound 1) has been synthesized and evaluated as an anti-hypertension agent, which exhibits extraordinary effects on the contractile response of thoracic aorta rings from male SD rats in vitro (IC(50) = 1.129×10(-9)±0.5025) and the abilities of reducing the...

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Detalles Bibliográficos
Autores principales:	Zhu, Kai, Yang, Su-Na, Ma, Fen-Fen, Gu, Xian-Feng, Zhu, Yi-Chun, Zhu, Yi-Zhun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409389/ https://www.ncbi.nlm.nih.gov/pubmed/25909998 http://dx.doi.org/10.1371/journal.pone.0119477

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