Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells

Enhancers regulate spatiotemporal gene expression and impart cell-specific transcriptional outputs that drive cell identity(1). Stretch- or super-enhancers (SEs) are a subset of enhancers especially important for genes associated with cell identity and genetic risk of disease(2,3,4,5,6). CD4(+) T ce...

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Detalles Bibliográficos
Autores principales: Vahedi, Golnaz, Kanno, Yuka, Furumoto, Yasuko, Jiang, Kan, Parker, Stephen C., Erdos, Michael, Davis, Sean R., Roychoudhuri, Rahul, Restifo, Nicholas P., Gadina, Massimo, Tang, Zhonghui, Ruan, Yijun, Collins, Francis S., Sartorelli, Vittorio, O’Shea, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409450/
https://www.ncbi.nlm.nih.gov/pubmed/25686607
http://dx.doi.org/10.1038/nature14154

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