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A locus on mouse Chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells
Invariant natural killer T (iNKT)-cell development is controlled by many polymorphic genes present in commonly used mouse inbred strains. Development of type 1 diabetes (T1D) in NOD mice partly results from their production of fewer iNKT-cells compared to non-autoimmune prone control strains includi...
Autores principales: | Tsaih, Shirng-Wern, Presa, Maximiliano, Khaja, Shamim, Ciecko, Ashley E., Serreze, David V., Chen, Yi-Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409484/ https://www.ncbi.nlm.nih.gov/pubmed/25654212 http://dx.doi.org/10.1038/gene.2014.81 |
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