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Structure of the TRPA1 ion channel suggests regulatory mechanisms
The TRPA1 ion channel (a.k.a the ‘wasabi receptor’) is a detector of noxious chemical agents encountered in our environment or produced endogenously during tissue injury or drug metabolism. These include a broad class of electrophiles that activate the channel through covalent protein modification....
Autores principales: | Paulsen, Candice E., Armache, Jean-Paul, Gao, Yuan, Cheng, Yifan, Julius, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409540/ https://www.ncbi.nlm.nih.gov/pubmed/25855297 http://dx.doi.org/10.1038/nature14367 |
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