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Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy

PURPOSE: The purpose of this study was to assess indications for stereotactic vacuum-assisted breast biopsy (SVAB) evaluated by breast 3 T-magnetic resonance (3 T-MR) imaging in patients showing suspicious microcalcifications on mammography and negative ultrasound (US) findings. METHODS AND MATERIAL...

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Autores principales: Yamamoto, Nobuko, Yoshizako, Takeshi, Yoshikawa, Kazuaki, Itakura, Masayuki, Maruyama, Riruke, Kitagaki, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409605/
https://www.ncbi.nlm.nih.gov/pubmed/25932356
http://dx.doi.org/10.1186/2193-1801-3-481
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author Yamamoto, Nobuko
Yoshizako, Takeshi
Yoshikawa, Kazuaki
Itakura, Masayuki
Maruyama, Riruke
Kitagaki, Hajime
author_facet Yamamoto, Nobuko
Yoshizako, Takeshi
Yoshikawa, Kazuaki
Itakura, Masayuki
Maruyama, Riruke
Kitagaki, Hajime
author_sort Yamamoto, Nobuko
collection PubMed
description PURPOSE: The purpose of this study was to assess indications for stereotactic vacuum-assisted breast biopsy (SVAB) evaluated by breast 3 T-magnetic resonance (3 T-MR) imaging in patients showing suspicious microcalcifications on mammography and negative ultrasound (US) findings. METHODS AND MATERIALS: Fifty-five patients with 55 breast lesions showing suspicious microcalcifications on mammography and negative US findings underwent preoperative 3 T-MR examination including dynamic MR imaging. All patients underwent SVAB within 1 month of MR imaging. The pathological diagnosis of each breast lesion was made by examining tissues obtained by SVAB or radical/partial mastectomy. 3 T-MR imaging findings were evaluated by using the American College of Radiology Breast Imaging Reporting and Data System Atlas (BI-RADS-MRI) and then were correlated with the histopathological findings. When BI-RADS 4 and 5 MR imaging lesions were assumed to be malignant, the usefulness of 3 T-MR imaging was evaluated for diagnosis of impalpable breast lesions by SVAB among lesions with microcalcification detected by mammography and negative US findings. RESULTS: There were 21 malignant lesions, including 5 invasive ductal carcinomas, 16 lesions of ductal carcinoma in situ (DCIS). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 3 T-MR imaging for deciding the indications for SVAB was 90.5%, 97.1%, 95.0%, 94.3%, and 94.5%, respectively. The one-false negative case was a DCIS with small enhancing lesions (0.5 mm). The one false-positive case was ductal adenoma with a linear ductal pattern of enhancement. CONCLUSIONS: 3 T-MR imaging may be useful for deciding the indications for SVAB in patients who have breast lesions with microcalcification that are impalpable and are detected by mammography and negative US findings. However, our findings should be considered preliminary and further prospective investigation is required.
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spelling pubmed-44096052015-04-30 Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy Yamamoto, Nobuko Yoshizako, Takeshi Yoshikawa, Kazuaki Itakura, Masayuki Maruyama, Riruke Kitagaki, Hajime Springerplus Research PURPOSE: The purpose of this study was to assess indications for stereotactic vacuum-assisted breast biopsy (SVAB) evaluated by breast 3 T-magnetic resonance (3 T-MR) imaging in patients showing suspicious microcalcifications on mammography and negative ultrasound (US) findings. METHODS AND MATERIALS: Fifty-five patients with 55 breast lesions showing suspicious microcalcifications on mammography and negative US findings underwent preoperative 3 T-MR examination including dynamic MR imaging. All patients underwent SVAB within 1 month of MR imaging. The pathological diagnosis of each breast lesion was made by examining tissues obtained by SVAB or radical/partial mastectomy. 3 T-MR imaging findings were evaluated by using the American College of Radiology Breast Imaging Reporting and Data System Atlas (BI-RADS-MRI) and then were correlated with the histopathological findings. When BI-RADS 4 and 5 MR imaging lesions were assumed to be malignant, the usefulness of 3 T-MR imaging was evaluated for diagnosis of impalpable breast lesions by SVAB among lesions with microcalcification detected by mammography and negative US findings. RESULTS: There were 21 malignant lesions, including 5 invasive ductal carcinomas, 16 lesions of ductal carcinoma in situ (DCIS). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 3 T-MR imaging for deciding the indications for SVAB was 90.5%, 97.1%, 95.0%, 94.3%, and 94.5%, respectively. The one-false negative case was a DCIS with small enhancing lesions (0.5 mm). The one false-positive case was ductal adenoma with a linear ductal pattern of enhancement. CONCLUSIONS: 3 T-MR imaging may be useful for deciding the indications for SVAB in patients who have breast lesions with microcalcification that are impalpable and are detected by mammography and negative US findings. However, our findings should be considered preliminary and further prospective investigation is required. Springer International Publishing 2014-08-28 /pmc/articles/PMC4409605/ /pubmed/25932356 http://dx.doi.org/10.1186/2193-1801-3-481 Text en © Yoshizako et al.; licensee Springer. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Research
Yamamoto, Nobuko
Yoshizako, Takeshi
Yoshikawa, Kazuaki
Itakura, Masayuki
Maruyama, Riruke
Kitagaki, Hajime
Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy
title Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy
title_full Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy
title_fullStr Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy
title_full_unstemmed Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy
title_short Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy
title_sort breast 3 t-mr imaging: indication for stereotactic vacuum-assisted breast biopsy
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409605/
https://www.ncbi.nlm.nih.gov/pubmed/25932356
http://dx.doi.org/10.1186/2193-1801-3-481
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