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Development of a serological assay to predict antibody bactericidal activity against non-typeable Haemophilus influenzae

BACKGROUND: Non-typeable Haemophilus influenzae (NTHi) is a Gram negative microorganism residing in the human nasopharyngeal mucosa and occasionally causing infections of both middle ear and lower respiratory airways. A broadly protective vaccine against NTHi has been a long-unmet medical need, as t...

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Detalles Bibliográficos
Autores principales: Ercoli, Giuseppe, Baddal, Buket, Alessandra, Greco, Marchi, Sara, Petracca, Roberto, Aricò, Beatrice, Pizza, Mariagrazia, Soriani, Marco, Rossi-Paccani, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409741/
https://www.ncbi.nlm.nih.gov/pubmed/25927946
http://dx.doi.org/10.1186/s12866-015-0420-x