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A product of independent beta probabilities dose escalation design for dual-agent phase I trials
Dual-agent trials are now increasingly common in oncology research, and many proposed dose-escalation designs are available in the statistical literature. Despite this, the translation from statistical design to practical application is slow, as has been highlighted in single-agent phase I trials, w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409822/ https://www.ncbi.nlm.nih.gov/pubmed/25630638 http://dx.doi.org/10.1002/sim.6434 |