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The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lpr Mice
OBJECTIVE: The hygiene hypothesis suggests that parasitic helminths (worms) protect against the development of autoimmune disease via a serendipitous side effect of worm-derived immunomodulators that concomitantly promote parasite survival and limit host pathology. The aim of this study was to inves...
Autores principales: | Rodgers, David T, McGrath, Mairi A, Pineda, Miguel A, Al-Riyami, Lamyaa, Rzepecka, Justyna, Lumb, Felicity, Harnett, William, Harnett, Margaret M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409857/ https://www.ncbi.nlm.nih.gov/pubmed/25546822 http://dx.doi.org/10.1002/art.39004 |
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