TM-233, a novel analog of 1′-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities

Although the introduction of bortezomib and immunomodulatory drugs has led to improved outcomes in patients with multiple myeloma, the disease remains incurable. In an effort to identify more potent and well-tolerated agents for myeloma, we have previously reported that 1′-acetoxychavicol acetate (A...

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Detalles Bibliográficos
Autores principales: Sagawa, Morihiko, Tabayashi, Takayuki, Kimura, Yuta, Tomikawa, Tatsuki, Nemoto-Anan, Tomoe, Watanabe, Reiko, Tokuhira, Michihide, Ri, Masaki, Hashimoto, Yuichi, Iida, Shinsuke, Kizaki, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409888/
https://www.ncbi.nlm.nih.gov/pubmed/25613668
http://dx.doi.org/10.1111/cas.12616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409888/
https://www.ncbi.nlm.nih.gov/pubmed/25613668
http://dx.doi.org/10.1111/cas.12616

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